Exploration of simultaneous dual-isotope imaging with a multiphoton modular J-PET scanner

被引:13
作者
Beyene, Ermias Y. [1 ,2 ,3 ,4 ]
Das, Manish [3 ,4 ]
Durak-Kozica, Martyna [3 ,4 ]
Korcyl, Grzegorz [3 ,4 ]
Mryka, Wiktor [3 ,4 ]
Niedzwiecki, Szymon [3 ,4 ]
Parzych, Szymon [3 ,4 ]
Tayefi, Keyvan [3 ,4 ]
Walczak, Rafal [5 ]
Wawrowicz, Kamil [3 ,4 ]
Stepien, Ewa [3 ,4 ]
Moskal, Pawel [3 ,4 ]
机构
[1] Jagiellonian Univ, Doctoral Sch Exact & Nat Sci, Larasiewicza St 11, PL-30348 Krakow, Poland
[2] Jagiellonian Univ Krakow, Dept Expt Particle Phys & Applicat, Krakow, Poland
[3] Jagiellonian Univ, Fac Phys Astron & Appl Comp Sci, Krakow, Poland
[4] Jagiellonian Univ, Ctr Theranost, Krakow, Poland
[5] Ctr Radiochem & Nucl Chem, Inst Nucl Chem & Technol, Warsaw, Poland
关键词
Dual isotope imaging; beta(+) + gamma imaging; 2 gamma imaging; medical imaging; J-PET; PET; multiphoton PET; POSITRONIUM;
D O I
10.5604/01.3001.0054.1940
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The modular J-PET scanner, comprising 24 compact and versatile modules, each consisting of 13 plastic strips with four SiPM detectors at the ends, represents a powerful tool for clinical applications in nuclear medical imaging. This study presents preliminary results from the exploration of simultaneous dual-isotope imaging using the modular J-PET system. Our approach involved two isotopes: Ge-68, characterized by a ringlike shape, and Na-22, exhibiting a point-like shape. The imaging was based on double-coincidence and triple-coincidence events. In the double coincidence case, both isotopes contributed comparably, whereas in the triple coincidence case Na-22 dominated due to the prompt gamma being emitted with 100% of positron emissions, unlike Ga-68, where the prompt gamma was emitted in only 1.3% of cases after positron emission. In this work we present direct 2 gamma images determined for two-signal events and images for three-signal events, with two signals from annihilation photons and one from a prompt gamma. These results showcase the preliminary findings from simultaneous dual-isotope imaging of Ga-68 and Na-22 isotopes using the modular J-PET scanner, which will be presented and discussed.
引用
收藏
页码:101 / 108
页数:8
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