Fast and controllable preparation of core-shell microfibers by 3D printing microfluidic device

被引：0

作者：

Ma W. ^{[1
]}

Chen Z. ^{[1
]}

Ling S. ^{[1
]}

Zhang J. ^{[1
]}

Xu J. ^{[1
]}

机构：

[1] Department of Chemical Engineering, State Key Laboratory of Chemical Engineering, Tsinghua University, Beijing

来源：

Huagong Xuebao/CIESC Journal | 2022年 / 73卷 / 01期

关键词：

3D printing; Fiber; Microchannels; Microfluidics; Multiphase flow;

D O I：

10.11949/0438-1157.20210884

中图分类号：

学科分类号：

摘要：

Through 3D printing technology, a microfluidic channel capable of spinning core-shell calcium alginate microfibers was quickly prepared, and precise control of the fiber morphology and structure was achieved. The effects of three phase flow rates, solution viscosity, channel height and undertake tube length on the morphology and structure of the prepared fibers were studied. The experimental results show that compared with other methods, the 3D printing method is more convenient and stable for the preparation of spinning channels, and the batch stability of the channels is high, so it is suitable for the mass production of microfibers. For the morphology control of the fibers, increasing the outer phase velocity can reduce the fiber diameter, increasing the middle phase velocity can increase the shell thickness, and increasing the inner phase velocity can increase the diameter of the nucleus. The change of solution viscosity has little effect on the fiber morphology. The greater the distance between the outlet of the microchannel and the solidification liquid, the thinner the fiber. If the length of the receiving tube is too short, the fiber will be uneven. The core-shell structure of fibers makes it easy to load functional substances and has potential application in the field of drug delivery. © 2022, Editorial Board of CIESC Journal. All right reserved.

引用

页码：434 / 440

页数：6

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