Recent advances in the application of [2+2] cycloaddition in the chemical synthesis of cyclobutane-containing natural products

被引：3
|
作者：
Hou, Song-Yu [1 ]
Yan, Bing-Chao [1 ]
Sun, Han-Dong [1 ]
Puno, Pema-Tenzin [1 ]
机构：
[1] Chinese Acad Sci, Univ Chinese Acad Sci, Kunming Inst Bot, Key Lab Phytochemistry & Nat Med, Kunming 650201, Yunnan, Peoples R China
来源：
NATURAL PRODUCTS AND BIOPROSPECTING | 2024年 / 14卷 / 01期
关键词：
2+2] Cycloaddition; Total synthesis; Natural products; Cyclobutane; ENANTIOSELECTIVE TOTAL SYNTHESES; KETENIMINIUM SALTS; CYCLO-ADDITIONS; LEWIS-ACID; KETENE; DERIVATIVES; ARYLATION; SKELETON; PHOTOCATALYSIS; SESQUITERPENE;
D O I：
10.1007/s13659-024-00457-9
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Cyclobutanes are distributed widely in a large class of natural products featuring diverse pharmaceutical activities and intricate structural frameworks. The [2 + 2] cycloaddition is unequivocally the primary and most commonly used method for synthesizing cyclobutanes. In this review, we have summarized the application of the [2 + 2] cycloaddition with different reaction mechanisms in the chemical synthesis of selected cyclobutane-containing natural products over the past decade.
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页数：23
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