Organs-at-risk dose and normal tissue complication probability with dynamic trajectory radiotherapy (DTRT) for head and neck cancer

被引：7

作者：

Bertholet, Jenny ^{[1
,2
]}

Mackeprang, Paul-Henry ^{[1
]}

Loebner, Hannes A. ^{[1
]}

Mueller, Silvan ^{[1
]}

Guyer, Gian ^{[1
]}

Frei, Daniel ^{[1
]}

Volken, Werner ^{[1
]}

Elicin, Olgun ^{[1
]}

Aebersold, Daniel M. ^{[1
]}

Fix, Michael K. ^{[1
]}

Manser, Peter ^{[1
]}

机构：

[1] Bern Univ Hosp, Univ Bern, Dept Radiat Oncol, Div Med Radiat Phys, Bern, Switzerland

[2] Univ Hosp Bern, Inselspital, Freiburgstr, CH-3010 Bern, Switzerland

来源：

RADIOTHERAPY AND ONCOLOGY | 2024年 / 195卷

关键词：

Head and neck cancer; Dynamic trajectory radiotherapy; VMAT; Treatment planning; NTCP; VOLUMETRIC-MODULATED ARC; SQUAMOUS-CELL CARCINOMA; RADIATION-THERAPY; FILM DOSIMETRY; BRAIN; OPTIMIZATION; CHEMOTHERAPY; DELINEATION; QUALITY; UPDATE;

D O I：

10.1016/j.radonc.2024.110237

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We compared dynamic trajectory radiotherapy (DTRT) to state-of-the-art volumetric modulated arc therapy (VMAT) for 46 head and neck cancer cases. DTRT had lower dose to salivary glands and swallowing structure, resulting in lower predicted xerostomia and dysphagia compared to VMAT. DTRT is deliverable on C -arm linacs with high dosimetric accuracy.

引用

页数：5

共 48 条

[1] Fatigue in Patients With Head and Neck Cancer Treated With Radiation Therapy: A Prospective Study of Patient-Reported Outcomes and Their Association With Radiation Dose to the Cerebellum [J].

Abel, Edvard ;

Silander, Ewa ;

Nordstrom, Fredrik ;

Olsson, Caroline ;

Brodin, N. Patrik ;

Nyman, Jan ;

Bjork-Eriksson, Thomas ;

Hammerlid, Eva .

ADVANCES IN RADIATION ONCOLOGY, 2022, 7 (05)

[2] Very late xerostomia, dysphagia, and neck fibrosis after head and neck radiotherapy [J].

Baudelet, Margot ;

Van den Steen, Leen ;

Tomassen, Peter ;

Bonte, Katrien ;

Deron, Philippe ;

Huvenne, Wouter ;

Rottey, Sylvie ;

De Neve, Wilfried ;

Sundahl, Nora ;

Van Nuffelen, Gwen ;

Duprez, Frederic .

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2019, 41 (10) :3594-3603

[3] Organ-at-risk sparing with dynamic trajectory radiotherapy for head and neck cancer: comparison with volumetric arc therapy on a publicly available library of cases [J].

Bertholet, Jenny ;

Mackeprang, Paul-Henry ;

Mueller, Silvan ;

Guyer, Gian ;

Loebner, Hannes A. ;

Wyss, Yanick ;

Frei, Daniel ;

Volken, Werner ;

Elicin, Olgun ;

Aebersold, Daniel M. ;

Fix, Michael K. ;

Manser, Peter .

RADIATION ONCOLOGY, 2022, 17 (01)

[4] Concomitant chemoradiotherapy versus acceleration of radiotherapy with or without concomitant chemotherapy in locally advanced head and neck carcinoma (GORTEC 99-02): an open-label phase 3 randomised trial [J].

Bourhis, Jean ;

Sire, Christian ;

Graff, Pierre ;

Gregoire, Vincent ;

Maingon, Philippe ;

Calais, Gilles ;

Gery, Bernard ;

Martin, Laurent ;

Alfonsi, Marc ;

Desprez, Patrick ;

Pignon, Thierry ;

Bardet, Etienne ;

Rives, Michel ;

Geoffrois, Lionel ;

Daly-Schveitzer, Nicolas ;

Sen, Sok ;

Tuchais, Claude ;

Dupuis, Olivier ;

Guerif, Stephane ;

Lapeyre, Michel ;

Favrel, Veronique ;

Hamoir, Marc ;

Lusinchi, Antoine ;

Temam, Stephane ;

Pinna, Antonella ;

Tao, Yun Gan ;

Blanchard, Pierre ;

Auperin, Anne .

LANCET ONCOLOGY, 2012, 13 (02) :145-153

[5] Identifying patients who may benefit from adaptive radiotherapy: Does the literature on anatomic and dosimetric changes in head and neck organs at risk during radiotherapy provide information to help? [J].

Brouwer, Charlotte L. ;

Steenbakkers, Roe J. H. M. ;

Langendijk, Johannes A. ;

Sijtsema, Nanna M. .

RADIOTHERAPY AND ONCOLOGY, 2015, 115 (03) :285-294

[6] Patterns of long-term swallowing dysfunction after definitive radiotherapy or chemoradiation [J].

Christianen, Miranda E. M. C. ;

Verdonck-de Leeuw, Irma M. ;

Doornaert, Patricia ;

Chouvalova, Olga ;

Steenbakkers, Roel J. H. M. ;

Koken, Phil W. ;

Leemans, C. Rene ;

Oosting, Sjoukje F. ;

Roodenburg, Jan L. N. ;

van der Laan, Bernard F. A. M. ;

Slotman, Ben J. ;

Bijl, Hendrik P. ;

Langendijk, Johannes A. .

RADIOTHERAPY AND ONCOLOGY, 2015, 117 (01) :139-144

[7] Randomized clinical trial on reduction of radiotherapy dose to the elective neck in head and neck squamous cell carcinoma; update of the long-term tumor outcome [J].

Deschuymer, Sarah ;

Nevens, Daan ;

Duprez, Frederic ;

Daisne, Jean-Francois ;

Dok, Ruveyda ;

Laenen, Annouschka ;

Voordeckers, Mia ;

De Neve, Wilfried ;

Nuyts, Sandra .

RADIOTHERAPY AND ONCOLOGY, 2020, 143 :24-29

[8] The influence of xerostomia after radiotherapy on quality of life [J].

Dirix, Piet ;

Nuyts, Sandra ;

Poorten, Vincent Vander ;

Delaere, Pierre ;

Van den Bogaert, Walter .

SUPPORTIVE CARE IN CANCER, 2008, 16 (02) :171-179

[9] Part 1: Optimization and evaluation of dynamic trajectory radiotherapy [J].

Fix, Michael K. ;

Frei, Daniel ;

Volken, Werner ;

Terribilini, Dario ;

Mueller, Silvan ;

Elicin, Olgun ;

Hemmatazad, Hossein ;

Aebersold, Daniel M. ;

Manser, Peter .

MEDICAL PHYSICS, 2018, 45 (09) :4201-4212

[10] Dosimetric comparison of coplanar and non-coplanar volumetric-modulated arc therapy in head and neck cancer treated with radiotherapy [J].

Gayen, Sanjib ;

Kombathula, Harsha ;

Manna, Sumanta ;

Varshney, Sonal ;

Pareek, Puneet .

RADIATION ONCOLOGY JOURNAL, 2020, 38 (02) :138-147

← 1 2 3 4 5 →