Analysis and Reporting of Adverse Drug Reactions of Cosmetics at a Tertiary Care Hospital

被引:0
作者
Paikray, Elisha [1 ]
Bisoyi, Diptiranjani [2 ]
Rout, Anima [1 ]
Mishra, Vedvyas [3 ]
机构
[1] Kalinga Inst Ind Technol KIIT Univ, Kalinga Inst Med Sci, Pharmacol, Bhubaneswar, India
[2] SCB Srirama Chandra Bhanja Med Coll & Hospital, Skin & Venereal Dis, Cuttack, India
[3] SCB Srirama Chandra Bhanja Med Coll & Hospital, Pharmacol, Cuttack, India
关键词
product lifestyle management; pharmaco-vigilance; adverse drug reactions; colipa method; cosmeto-; vigilance; COSMETOVIGILANCE SURVEY; PRODUCTS; TOILETRIES; UNIVERSITY; EVENTS; NEED;
D O I
10.7759/cureus.56856
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and objectives Cosmetovigilance is a term used for the activities related to the collection, evaluation, and monitoring of spontaneous reports of undesirable events observed during or after normal or reasonably foreseeable use of a cosmetic product. It is now considered a part of the public health system to determine the toxicity of cosmetic products. India has a pharmacovigilance system that monitors adverse drug reactions. Adverse effects due to the use of cosmetic products are undernumbered and a rigorous vigilant system is necessary to check the unmet needs of our country. Hence keeping the above in view, the study was conducted. Material and methods Patients of any gender, aged above 18 years, reporting adverse reactions to cosmetics at the study site were included in the study. The adverse reactions to cosmetics were noted. The causality of the observed adverse cosmetic reactions (ACRs) was done by the European Cosmetic, Toiletry and Perfumery Association (COLIPA) and Product Lifecycle Management (PLM) methods. Results A total of 120 patients were included in the study. The cosmetic products used by the patients were mainly face care products (n=144) followed by make-up care products (n=126). A total of 121 types of ACRs were reported. The majority of the ACRs were caused by products involved in facial care (62; 51.2%) followed by personal care products (20; 16.5%). In the causality assessment of the ACRs using the COLIPA method, 49.4% of patients were categorized as likely, and using the PLM method, 59% of the events were categorized as probable. Conclusion Most of the ACRs were caused by face care products and acne was reported as the most frequently occurring ACR. Awareness programs regarding the reporting of ACRs should be encouraged among cosmetic users and stakeholders.
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页数:7
相关论文
共 27 条
[1]   Allergy to Cosmetics: A Literature Review [J].
Alani, Jennifer I. ;
Davis, Mark Denis P. ;
Yiannias, James A. .
DERMATITIS, 2013, 24 (06) :283-290
[2]   Stearic Acid Accumulation in Macrophages Induces Toll-Like Receptor 4/2-Independent Inflammation Leading to Endoplasmic Reticulum Stress-Mediated Apoptosis [J].
Anderson, Emily K. ;
Hill, Andrea A. ;
Hasty, Alyssa H. .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2012, 32 (07) :1687-1695
[3]   Safety of botanical ingredients in personal care products/cosmetics [J].
Antignac, Eric ;
Nohynek, Gerhard J. ;
Re, Thomas ;
Clouzeau, Jacques ;
Toutain, Herve .
FOOD AND CHEMICAL TOXICOLOGY, 2011, 49 (02) :324-341
[4]   Adverse effects of cosmetics and toiletries reported to the Swedish Medical Products Agency 1989-1994 [J].
Berne, B ;
Bostrom, A ;
Grahnen, AF ;
Tammela, M .
CONTACT DERMATITIS, 1996, 34 (05) :359-362
[5]   Cosmetics Use-Related Adverse Events and Determinants Among Jigjiga Town Residents, Eastern Ethiopia [J].
Bilal, Arebu I. ;
Tilahun, Zelalem ;
Osman, Ebrahim D. ;
Mulugeta, Anwar ;
Shekabdulahi, Muktar ;
Berhe, Derbew Fikadu .
DERMATOLOGY AND THERAPY, 2017, 7 (01) :143-153
[6]  
Bons B, 2010, Regul Toxicol Pharmacol, V58, P349, DOI 10.1016/j.yrtph.2010.06.015
[7]   Clinical manifestations and impact on daily life of allergy to polyethylene glycol (PEG) in ten patients [J].
Bruusgaard-Mouritsen, Maria A. ;
Johansen, Jeanne D. ;
Garvey, Lene H. .
CLINICAL AND EXPERIMENTAL ALLERGY, 2021, 51 (03) :463-470
[8]   ADVERSE-EFFECTS OF COSMETICS AND TOILETRIES - A RETROSPECTIVE STUDY IN THE GENERAL-POPULATION [J].
DEGROOT, AC ;
NATER, JP ;
VANDERLENDE, R ;
RIJCKEN, B .
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, 1987, 9 (06) :255-259
[9]   Cosmetovigilance survey: Are cosmetics considered safe by consumers? [J].
Di Giovanni, C ;
Arcoraci, V ;
Gambardella, L ;
Sautebin, L .
PHARMACOLOGICAL RESEARCH, 2006, 53 (01) :16-21
[10]   Cosmetic Use and Its Adverse Events among Female Employees of Jimma University, Southwest Ethiopia [J].
Getachew, Mestawet ;
Tewelde, Tsegaye .
ETHIOPIAN JOURNAL OF HEALTH SCIENCES, 2018, 28 (06) :717-724