Human papillomavirus and Epstein-Barr virus infection in benign thyroid lesions

被引：1

作者：

Lu, Yingying ^{[1
]}

Zhao, Runyu ^{[2
]}

Zhang, Yi ^{[3
]}

Huang, Shuixian ^{[3
]}

Chen, Xiaoping ^{[3
]}

机构：

[1] Shanghai Univ, Sch Med, Shanghai, Peoples R China

[2] Ningxia Med Univ, Shanghai Gongli Hosp, Postgrad Training Base, Shanghai, Peoples R China

[3] Gongli Hosp, Shanghai Pudong New Area, Dept Orthoped, Miaopu Rd 219, Shanghai 200135, Peoples R China

来源：

ENDOKRYNOLOGIA POLSKA | 2024年 / 75卷 / 02期

关键词：

Hashimoto's thyroiditis; thyroid adenoma; EB virus; human papilloma virus; ADENOMAS;

D O I：

10.5603/ep.99339

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: The objective was to investigate the correlation between Epstein -Barr virus (EBV) and human papillomavirus (HPV) infection in the development of benign thyroid lesions. Material and methods: 29 cases of Hashimoto's thyroiditis (HT), 133 cases of thyroid adenoma, and 34 cases of HT with thyroid adenoma paraffin embedded tissue samples were used for EBV and HPV quantitative detection. Results: None of the tissue samples carried HPV DNA. In HT tissue samples, the positive rate of EBV was 55.2% (16/29). In thyroid adenoma tissue samples, the positive rate was 37.6% (50/133). In HT combined with thyroid adenoma tissue samples, the positive rate of EBV was 67.6% (23/34). There was no correlation between EBV infection and clinical features such as age and gender. Conclusion: The occurrence and development of benign thyroid lesions are closely related to EBV infection. HT combined with thyroid adenoma may be more susceptible to EBV infection than simple HT and thyroid adenoma, which provides a new idea for the diagnosis and treatment of benign thyroid lesions.

引用

页码：179 / 182

页数：4

共 16 条

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