Improved skin regeneration with acellular fish skin grafts

被引：48

作者：

Fiakos G. ^{[1
]}

Kuang Z. ^{[1
]}

Lo E. ^{[1
]}

机构：

[1] Stony Brook University, Biomedical Engineering, 100 Nicolls Rd, Stony Brook, 11794, NY

来源：

Engineered Regeneration | 2020年 / 1卷

关键词：

Burn wounds; Chronic wounds; Omega-3 polyunsaturated fatty acid; Skin xenografts; Wound healing;

D O I：

10.1016/j.engreg.2020.09.002

中图分类号：

学科分类号：

摘要：

Fish skin graft, a novel skin substitute, has seen a widespread clinical application since the approval for wound coverage by the FDA. Due to its properties in promoting wound healing and its efficient cost in manufacturing, fish skin grafts are a potential alternative to allograft and xenograft sources including, but not limited to cadaver and porcine grafts in a variety of applications. Additionally, fish skin grafts show promising results in treating diabetic foot ulcers (DFUs), venous leg ulcers (VLUs) and some evidence worthy of further exploration in treating a host of other acute and chronic wounds. Here we summarize the material and biological properties of fish skin grafts. How this graft compares to other prevailing skin substitutes on the market for different wound types was also explored. Fish skin grafts have many uses in clinical applications of the future. © 2020 KeAi Communications Co., Ltd

引用

页码：95 / 101

页数：6

共 52 条

[21]

Huang T.-H., Et al., Cosmetic and therapeutic applications of fish oil's fatty acids on the skin, Mar. Drugs, 16, 8, (2018)

[22]

Prevention C.F.D.C.A., National Diabetes Statistics Report, (2020)

[23]

Driver V.R., Et al., The costs of diabetic foot: the economic case for the limb salvage team, J Vasc Surg, 52, 3, pp. 17S-22S, (2010)

[24]

Falanga V., Wound healing and its impairment in the diabetic foot, Lancet, 366, 9498, pp. 1736-1743, (2005)

[25]

Liu Y., Et al., Increased matrix metalloproteinase-9 predicts poor wound healing in diabetic foot ulcers, Diab. Care, 32, 1, pp. 117-119, (2009)

[26]

Van Doren S.R., Matrix metalloproteinase interactions with collagen and elastin, Matrix Biol.: J. Int.Soc. Matrix Biol., 44-46, pp. 224-231, (2015)

[27]

Zhou T., Et al., Multifunctional and biomimetic fish collagen/bioactive glass nanofibers: fabrication, antibacterial activity and inducing skin regeneration in vitro and in vivo, Int. J. Nanomed., 12, pp. 3495-3507, (2017)

[28]

Shin S.C., Et al., Characterization of two antimicrobial peptides from Antarctic fishes (Notothenia coriiceps and Parachaenichthys charcoti), PLoS ONE, 12, 1, (2017)

[29]

Woodrow T., Chant T., Chant H., Treatment of diabetic foot wounds with acellular fish skin graft rich in omega-3: a prospective evaluation, J. Wound Care, 28, 2, pp. 76-80, (2019)

[30]

Winters C., Wound dehiscence on a diabetic patient with haemophilia and high risk of further amputation successfully healed with omega-3 rich fish skin: a case report, Diab. Foot J., 21, 3, pp. 186-190, (2018)

← 1 2 3 4 5 6 →