Tuning the surface charge of phospholipid bilayers inhibits insulin fibrilization

被引：0
|
作者：
Reichelderfer, Victoria T. [1 ]
Chaparro Sosa, Andres F. [1 ]
Kaar, Joel L. [1 ]
Schwartz, Daniel K. [1 ]
机构：
[1] Department of Chemical and Biological Engineering, University of Colorado, Boulder,CO,80309, United States
来源：
Colloids and Surfaces B: Biointerfaces | 2022年 / 220卷
基金：
美国国家卫生研究院;
关键词：
Amyloid - Catanionic lipid - Fibril formation - Fibrilization - Phospholipids bilayer - Protein based therapeutics - Protein misfolding - Rational design - Small unilamellar vesicle - Structural state;
D O I：
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摘要：
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