Innovative Encapsulation Strategies for Food, Industrial, and Pharmaceutical Applications

被引:4
作者
Aanniz, Tarik [1 ]
El Omari, Nasreddine [2 ,3 ]
Elouafy, Youssef [4 ]
Benali, Taoufiq [5 ]
Zengin, Gokhan [6 ]
Khalid, Asaad [7 ,8 ]
Abdalla, Ashraf N. [9 ]
Sakran, Ashraf M. [10 ]
Bouyahya, Abdelhakim [11 ]
机构
[1] Mohammed V Univ Rabat, Bioinova Res Ctr, Rabat Med & Pharm Sch, Biotechnol Lab MedBiotech, Rabat 10100, Morocco
[2] High Inst Nursing Profess & Hlth Tech Tetouan, Tetouan, Morocco
[3] Mohammed V Univ Rabat, Fac Med & Pharm, Lab Histol Embryol & Cytogenet, Rabat 10100, Morocco
[4] Mohammed V Univ Rabat, Fac Sci, Lab Mat Nanotechnol & Environm LMNE, Rabat 1014, Morocco
[5] Cadi Ayyad Univ, Polydisciplinary Fac Safi, Environm & Hlth Team, Marrakech 46030, Morocco
[6] Selcuk Univ, Sci Fac, Dept Biol, TR-42130 Konya, Turkiye
[7] Jazan Univ, Subst Abuse & Toxicol Res Ctr, POB 114, Jazan 45142, Saudi Arabia
[8] Med & Aromat Plants & Tradit Med Res Inst, Natl Ctr Res, POB 2404, Khartoum, Sudan
[9] Umm Al Qura Univ, Coll Pharm, Dept Pharmacol & Toxicol, Mecca 21955, Saudi Arabia
[10] Umm Alqura Univ, Fac Med, Dept Anat, Mecca 21955, Saudi Arabia
[11] Mohammed V Univ Rabat, Fac Sci, Dept Biol, Lab Human Pathol Biol, Rabat 10106, Morocco
关键词
Encapsulation; spray-drying; essential oils; terpenoids; phenolic acids; efficiency; natural products; lipid carrier; CITRONELLA OIL MICROCAPSULES; SOLID LIPID NANOPARTICLES; LEMONGRASS ESSENTIAL OIL; OREGANO ESSENTIAL OIL; ANTIMICROBIAL ACTIVITY; ANTICANCER EFFICACY; BETA-CYCLODEXTRIN; POLYMERIC NANOPARTICLES; COMPLEX COACERVATION; LIPOSOMAL ENCAPSULATION;
D O I
10.1002/cbdv.202400116
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Bioactive metabolites obtained from fruits and vegetables as well as many drugs have various capacities to prevent or treat various ailments. Nevertheless, their efficiency, in vivo, encounter many challenges resulting in lower efficacy as well as different side effects when high doses are used resulting in many challenges for their application. Indeed, demand for effective treatments with no or less unfavorable side effects is rising. Delivering active molecules to a particular site of action within the human body is an example of targeted therapy which remains a challenging field. Developments of nanotechnology and polymer science have great promise for meeting the growing demands of efficient options. Encapsulation of active ingredients in nano-delivery systems has become as a vitally tool for protecting the integrity of critical biochemicals, improving their delivery, enabling their controlled release and maintaining their biological features. Here, we examine a wide range of nano-delivery techniques, such as niosomes, polymeric/solid lipid nanoparticles, nanostructured lipid carriers, and nano-emulsions. The advantages of encapsulation in targeted, synergistic, and supportive therapies are emphasized, along with current progress in its application. Additionally, a revised collection of studies was given, focusing on improving the effectiveness of anticancer medications and addressing the problem of antimicrobial resistance. To sum up, this paper conducted a thorough analysis to determine the efficacy of encapsulation technology in the field of drug discovery and development. + image
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页数:28
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