Ultra-low foetal radiation exposure in 18F-FDG PET/CT imaging with a long axial field-of-view PET/CT system

被引:4
|
作者
Smith, Charlotte L. C. [1 ,2 ]
Yaqub, Maqsood [1 ,2 ]
Wellenberg, Ruud H. H. [1 ]
Knip, Jelijn J. [2 ,3 ]
Boellaard, Ronald [1 ,2 ]
Zwezerijnen, Gerben J. C. [1 ,2 ]
机构
[1] Amsterdam UMC locat Vrije Univ Amsterdam, Dept Radiol & Nucl Med, NL-1117 Amsterdam, Netherlands
[2] Canc Ctr Amsterdam, Imaging & Biomarkers, Amsterdam, Netherlands
[3] Amsterdam UMC locat Vrije Univ Amsterdam, Dept Med Oncol, NL-1117 Amsterdam, Netherlands
来源
EJNMMI PHYSICS | 2024年 / 11卷 / 01期
关键词
Foetal radiation dose; Ultra-low PET/CT; LAFOV PET/CT; F-18-FDG PET; Pregnancy;
D O I
10.1186/s40658-024-00648-w
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose Long axial field-of-view (LAFOV) PET/CT systems enable PET/CT scans with reduced injected activities because of improved sensitivity. With this study, we aimed to examine the foetal radiation dose from an F-18-FDG PET/CT scan on a LAFOV PET/CT system with reduced injected activity. Methods Two pregnant women were retrospectively included and received an F-18-FDG PET/CT scan on a LAFOV PET/CT system with an intravenous bolus injection of 0.30 MBq/kg. Foetal radiation exposure from the PET was estimated using dose conversion factors from three published papers. Radiation exposure from the CT scans was estimated using CT-Expo. Results Foetal radiation dose from the PET scan ranged between 0.11 and 0.44 mGy. Foetal radiation exposure from the CT scan ranged between < 0.10 - 0.90 mGy depending if the foetus was included in the field-of-view. Conclusion Foetal radiation dose could be reduced to < 1.5 mGy when scanning pregnant patients on a LAFOV PET/CT system. The radiation dose to the foetus was reduced significantly in our study due to the increased sensitivity of the LAFOV PET/CT system.
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页数:5
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