Optimizing Antifungal Treatment Strategies to Prevent Invasive Pulmonary Aspergillosis Infection-Related Deaths in Intensive Care Unit Patients: The Need for Standardization of Research Definitions

被引：2

作者：

Bassetti, Matteo ^{[1
,2
]}

Vena, Antonio ^{[1
,2
]}

Bavastro, Martina ^{[1
,2
]}

Giacobbe, Daniele Roberto ^{[1
,2
]}

机构：

[1] IRCCS Osped Policlin San Martino, Infect Dis Unit, Genoa, Italy

[2] Univ Genoa, Dept Hlth Sci DISSAL, Via A Pastore 1, I-16132 Genoa, Italy

来源：

MYCOPATHOLOGIA | 2024年 / 189卷 / 04期

关键词：

Aspergillus; Invasive fungal diseases; Definitions; Invasive aspergillosis; ICU; IPA; BRONCHOALVEOLAR LAVAGE FLUID; FUNGAL-INFECTIONS; CRITICALLY-ILL; DIAGNOSIS; GALACTOMANNAN; DISEASE; TESTS; ICU;

D O I：

10.1007/s11046-024-00879-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The clinical spectrum of invasive pulmonary aspergillosis (IPA) has expanded in recent decades. A large group of patients admitted to intensive care units (ICU) is indeed susceptible to the development of IPA. Although timely diagnosis and antifungal therapy of IPA in this expanding population is crucial to prevent IPA-related deaths, the magnitude of the favorable prognostic impact of antifungal therapy is difficult to measure precisely. In our opinion, the development of standardized research definitions could have favorable implications for further improving our ability both to measure the favorable effect of antifungal treatment and to prevent IPA-related death in ICU patients.

引用

页数：6

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