Cross-linkable phosphonylcholine polymer modified polymethylpentene hollow fiber membrane

被引：0
作者：
Ye F. [1 ,2 ]
Yi G. [1 ]
机构：
[1] School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou
[2] Guangdong Shunde Industrial Design Institute (Guangdong Shunde Innovative Design Institute), Foshan
来源：
Yi, Guobin (yigb@gdut.edu.cn) | 1600年 / Beijing University of Aeronautics and Astronautics (BUAA)卷 / 38期
关键词：
Blood compatibility; Coating; Phosphorylcholine polymer; Polymethylpentene hollow fiber membrane (PMPHFM); Surface modification;
D O I：
10.13801/j.cnki.fhclxb.20200522.001
中图分类号：
学科分类号：
摘要：
Cross-linkable phosphorylcholine polymer (Poly(MPC-co-LMA-co-TSMA), PMLT) was prepared by free radical polymerization. Coating the copolymer solution on the surface of polymethylpentene hollow fiber membrane (PMPHFM) can form a stable polymer coating after the cross-linking treatment and obtain a modified composite material PMLT/PMPHFM. The swelling test shows that the PMLT copolymer has good hydrophilic properties, and the swelling degree increases with the increase of MPC content and temperature. ATR-FTIR and XPS analysis show that the polymer coating containing phosphorylcholine groups exist on the surface of PMLT/PMPHFM. SEM and fluorescence test results show that the surface of PMLT/PMPHFM is coated with a uniform polymer coating, and the coating could resist the dissolution of ethanol and SDS aqueous solution. Platelet adhesion and whole blood contact tests show that the coating could reduce platelet adhesion on the surface of PMPHFM, reduce the risk of blood clotting compared to bare PMPHFM. The results show that the PMLT copolymer has good hydrophilic property, and can be uniformly coated on the surface of PMPHFM to obtain a composite material PMLT/PMPHFM with good blood compatibility. Copyright ©2021 Acta Materiae Compositae Sinica. All rights reserved.
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页码：479 / 486
页数：7
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