Neuroprotective effect of sea urchins (Diadema savignyi) extract in an animal model of aluminum neurotoxicity

被引：0
作者：
Rofida Zagloul [1 ]
Eman A. Khalil [1 ]
Nada M. Ezzelarab [1 ]
Ahmed Abdellatif [1 ]
机构：
[1] The American University in Cairo,Department of Biology, School of Sciences and Engineering
来源：
Blue Biotechnology | / 1卷 / 1期
关键词：
Neurotoxicity; Neuroprotection; Sea urchin; Heavy metal toxicity; Aluminum toxicity; Oxidative stress; GFAP; Caspase 3;
D O I：
10.1186/s44315-024-00001-x
中图分类号：
学科分类号：
摘要：
Human exposure to heavy metals causes major health consequences. Aluminum (Al) toxicity primarily affects the brain and has been implicated in neurodegenerative disorders. Natural products offer a cheap and safe source of protective agents against heavy metal toxicity. This study investigates the neuroprotective role of the shell extract (SH) from the Sea urchin (Diadema savignyi) collected from the Red Sea in an Aluminum-induced neurotoxicity model.
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