AN SEIR EPIDEMIC MODEL WITH TWO INFECTIOUS PATHWAYS

被引:0
作者
Sangotola, A. O. [1 ]
Akinwumi, O. A. [1 ]
Nuga, O. A. [1 ]
Adebayo, E. A. [2 ]
Adeniji, A. E. [1 ]
Adigun, A. J. [2 ]
机构
[1] Bells Univ Technol, Dept Phys Sci, Ota, Nigeria
[2] Univ Delaware, Dept Math Sci, Newark, DE 19716 USA
关键词
Lyapunov function; equilibrium; basic reproduction number; stability; optimal control;
D O I
10.28919/cmbn/8089
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
In this research work, we present the mathematical framework of a SEIR epidemic model with two infectious pathways. The model is formulated by extending the classical SEIR mathematical model to involve two different but connected infectious states. The well posedness of the solutions of the system are shown. The basic reproduction number denoted by R-0 is computed through the next generation matrix method. The disease free equilibrium is asymptotically stable locally if R-0 < 1 and unstable otherwise while there exists a unique endemic equilibrium provided that R-0 > 1. The stability analysis for the disease free and endemic equilibrium is investigated by a suitable Lyapunov function globally. The effect of the parameters of the model on the basic reproduction number is measured by sensitivity analysis. Optimal control characterization analysis is also discussed. Some theoretical results obtained are also augmented through numerical simulation.
引用
收藏
页数:16
相关论文
共 11 条
[1]   GLOBAL DYNAMICS OF A GENERAL CLASS OF MULTISTAGE MODELS FOR INFECTIOUS DISEASES [J].
Guo, Hongbin ;
Li, Michael Y. ;
Shuai, Zhisheng .
SIAM JOURNAL ON APPLIED MATHEMATICS, 2012, 72 (01) :261-279
[3]  
Lasalle JP., 1976, The Stability of Dynamical Systems. Regional Conference Series in Applied Mathematics, DOI DOI 10.1137/1.9781611970432
[4]   Global asymptotic properties of an SEIRS model with multiple infectious stages [J].
Melesse, Dessalegn Y. ;
Gumel, Abba B. .
JOURNAL OF MATHEMATICAL ANALYSIS AND APPLICATIONS, 2010, 366 (01) :202-217
[5]   Qualitative analysis of a stochastic SEITR epidemic model with multiple stages of infection and treatment [J].
Otunuga, Olusegun Michael ;
Ogunsolu, Mobolaji O. .
INFECTIOUS DISEASE MODELLING, 2020, 5 :61-90
[6]  
Rifanti U. M., 2020, Journal of Physics: Conference Series, V1567, DOI 10.1088/1742-6596/1567/2/022075
[7]  
Sangotola A.O., 2022, Int. J. Math. Anal. Model., V5, P335
[8]   Global analysis of an SEIR model with varying population size and vaccination [J].
Sun, Chengjun ;
Hsieh, Ying-Hen .
APPLIED MATHEMATICAL MODELLING, 2010, 34 (10) :2685-2697
[9]   Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission [J].
van den Driessche, P ;
Watmough, J .
MATHEMATICAL BIOSCIENCES, 2002, 180 :29-48
[10]  
van den Driessche Pauline, 2017, Infect Dis Model, V2, P288, DOI 10.1016/j.idm.2017.06.002