Neural and Neural Crest-Derived Stem Cell Distribution in the Adult Human Dental Pulp

被引：0

作者：

Alzer, Heba ^{[1
]}

Abu Shahin, Nisreen ^{[2
]}

Alsoleihat, Firas ^{[1
,3
]}

机构：

[1] Univ Jordan, Sch Dent, Dept Restorat Dent, Amman 11942, Jordan

[2] Univ Jordan, Sch Med, Dept Pathol Microbiol & Forens Med, Amman 11942, Jordan

[3] Univ Petra, Fac Dent, Dept Restorat Dent & Basic Med Sci, Amman 11196, Jordan

来源：

INTERNATIONAL JOURNAL OF MORPHOLOGY | 2024年 / 42卷 / 02期

关键词：

NCAM1; Nestin; SNAIL/SLUG; SOX9; S100; Human dental pulp; Stem cells; Neural stem cells; Neural crest; SIDE POPULATION CELLS; IN-VITRO; TOOTH;

D O I：

暂无

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

Despite comprehensive studies and reports about the properties of dental pulp stem cells (DPSCs) in vitro, we still need to confirm whether these in vitro characteristics coincide with the nature of DPSCs in situ. The anatomical location of DPSCs populations in the dental pulp has yet to be investigated. Moreover, the mesenchymal DPSCs have been much more studied than the neural crest -derived DPSCs. In this study, well -recognized neural/neural crest stem cell markers NCAM1, Nestin, SNAIL/SLUG, SOX9, and S100 are being investigated by immunohistochemistry to localize the precise location of these populations of DPSCs within the human adult dental pulp. All previously mentioned markers were expressed in the dental pulp, and their intensity and location of expression were reported.

引用

页码：510 / 515

页数：6

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