Micro-Phase Separation Structure and Shape Memory Properties of Bio-Polyurethane/Hydroxyapatite

被引：0
|
作者：
Zhang P. [1 ]
Liu H. [1 ]
Wang Y. [1 ]
He S. [1 ,2 ]
Huang M. [1 ]
Liu W. [1 ]
Zhu C. [1 ]
机构：
[1] School of Materials Science and Engineering, Zhengzhou University, Zhengzhou
[2] Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou
来源：
Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering | 2020年 / 36卷 / 04期
关键词：
Bio-polyurethane; Bone repair; Hydroxyapatite; Microphase separation; Shape memory;
D O I：
10.16865/j.cnki.1000-7555.2020.0085
中图分类号：
学科分类号：
摘要：
Shape memory functionalized bio-polyurethane has attracted much attention in medical implant materials, and the shape memory performance of polyurethane is closely related to its micro-phase separation structure. In this study, polyurethane (PU) was synthesized by two-step process using degradable polycaprolactone diol (PCL-diol), alicyclic isophorone diisocyanate (IPDI), and 1,4-butanediol (BDO) as monomer. And a series of polyurethane/hydroxyapatite (PU/HA) composites were thus prepared by solution blending. The effects of HA on the microphase separation structure of PU matrix and its relationship to macroscopic shape memory performance were studied by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TG) and dynamic thermomechanical analysis (DMA). Moreover, the biosafety of the material was also examined by MTT cytotoxicity evaluation. Results show that the addition of HA significantly promotes the microphase separation of PU. The difference in the glass transition temperature between the hard segment and the soft segment increases as the increase of HA loading, which indicates the introduction of HA leads to a higher degree of microphase separation. Accordingly, the shape recovery performance increases as the increased loading of HA. The results of L929 cytotoxicity test show that PU/HA has good cell safety and potential application in the field of medical bone healing. © 2020, Editorial Board of Polymer Materials Science & Engineering. All right reserved.
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页码：119 / 127
页数：8
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