Diagnostic approaches for invasive mycoses: what's hot?

被引:1
作者
Lass-Floerl, Cornelia [1 ]
机构
[1] Med Univ Innsbruck, Direktorin Inst Hyg & Med Mikrobiol, Schopfstr 41, A-6020 Innsbruck, Austria
关键词
Biomarker; invasive mycoses; diagnostics; fungal microscopy; biomarker; CANDIDIASIS; GUIDELINES;
D O I
10.1055/a-2133-4826
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Invasive Pilzinfektionen sind eine wesentliche Ursache fur Morbiditat und Letalitat bei Patient*innen mit Abwehrschwache. Die wichtigsten und haufigsten Pathogene in Europa sind Aspergillus- und Candida- Spezies. Zunehmend werden aber auch Mucorales- , Trichosporon- und Fusarium- Spezies nachgewiesen. Die gesicherte Diagnose einer invasiven Mykose ist schwierig. Neben Bildgebung und Klinik sind Grundelemente der Diagnostik die konventionelle Pilzkultur, Mikroskopie, Antikorper-/Antigen-Suchtests und Molekularbiologie. Abstract Invasive fungal infections are a significant cause of morbidity and mortality in immunocompromised patients. The primary and most frequent pathogens in Europe are Aspergillus and Candida species. However, other representatives such as Mucorales, Trichosporon , and Fusarium species are increasingly being identified. Confirming the diagnosis of an invasive mycosis is challenging; apart from imaging and clinical presentation, essential diagnostic elements include conventional fungal culture, microscopy, antibody/antigen detection tests, and molecular biology.
引用
收藏
页码:551 / 559
页数:9
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