Optimization of ultrasound-assisted, microwave-assisted and Soxhlet extraction of bioactive compounds from Lagenaria siceraria: A comparative analysis

被引:31
作者
Abbas M. [1 ]
Ahmed D. [1 ]
Qamar M.T. [1 ]
Ihsan S. [1 ]
Noor Z.I. [1 ]
机构
[1] Department of Chemistry, Forman Christian College (A Chartered University), Lahore
来源
Bioresource Technology Reports | 2021年 / 15卷
关键词
Bioactive compounds; Extraction optimization; Lagenaria siceraria; MAE; SE; UAE;
D O I
10.1016/j.biteb.2021.100746
中图分类号
学科分类号
摘要
Lagenaria siceraria (LS) is recognized for its ethnomedicinal properties. The present study aimed to compare and optimize extraction of bioactive compounds, total phenolic content (TPC) and total flavonoid content (TFC) from LS by microwave-assisted extraction (MAE), ultrasound-assisted extraction (UAE) and Soxhlet extraction (SE) using ethyl acetate as a green solvent. The fresh fruit was ground and dried under two methods freeze drying and oven drying. The dried biomass was defatted with hexane and the defatted material was used for extraction. Maximum % yield by UAE, MAE and SE was 5.08%, 4.00% and 3.20%, respectively. The TPC (mg/100 mg of GAE) had the overall order as 32.02 of UAE >31.99 of MAE >16.51 of SE. The overall trend of the TFC (mg/100 mg of RE) was 24.28 of MAE >21.94 of UAE >7.94 of SE. In conclusion, for polyphenolic compounds from L. siceraria, UAE and MAE were highly more powerful than SE. © 2021 Elsevier Ltd
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