Effects of vitamin D3 on lifespan in Drosophila at different yeast levels

被引:1
作者
Jin, Hui [1 ]
Zhong, Lichao [1 ]
Xu, Yifan [1 ]
Shen, Jie [1 ]
机构
[1] Hangzhou Dianzi Univ, Coll Artificial Intelligence, Hangzhou 310018, Peoples R China
关键词
diet; Drosophila; longevity; sex difference; vitamin D3; STRESS-RESPONSE; D SUPPLEMENTS; D DEFICIENCY; HORMESIS; RISK;
D O I
10.1111/1748-5967.12729
中图分类号
Q96 [昆虫学];
学科分类号
摘要
Deficiency of vitamin D3 has been found to be associated with an increased risk of developing some common diseases and death. However, the exact effect of vitamin D3 intake along with a high-protein diet and its optimal intake is unclear. The purpose of this work is to evaluate the beneficial effects of vitamin D3 on longevity using the Drosophila model. Vitamin D3 did extend lifespan on a high-protein diet, but above a certain concentration, it had the opposite effect in males. Our data suggest that the effect of vitamin D3 on longevity is diet-dependent and concentration-dependent.
引用
收藏
页数:10
相关论文
共 50 条
  • [21] Inhibitory effects of imatinib on vitamin D3 synthesis in human keratinocytes
    Mehlig, Lysann Michaela
    Garve, Claudia
    Tauer, Josephine Tabea
    Suttorp, Meinolf
    Bauer, Andrea
    MOLECULAR MEDICINE REPORTS, 2015, 11 (04) : 3143 - 3147
  • [22] Vitamin D3 and its receptor in selected obstetrical complications
    Magielda-Stola, Justyna
    Drews, Krzysztof
    Wolski, Hubert
    Seremak-Mrozikiewicz, Agnieszka
    GINEKOLOGIA POLSKA, 2021, 92 (06) : 460 - 465
  • [23] Vitamin D3 as possible diagnostic marker of Eating Disorders
    La Bella, Vanessa
    Gizzi, Giulia
    Albi, Elisabetta
    Codini, Michela
    Marucci, Simonetta
    Dalla Ragione, Laura
    Beccari, Tommaso
    Ceccarini, Maria Rachele
    EUROBIOTECH JOURNAL, 2021, 5 (01) : 24 - 33
  • [24] Vitamin D3 metabolite ratio as an indicator of vitamin D status and its association with diabetes complications
    Ahmed, Lina H. M.
    Butler, Alexandra E.
    Dargham, Soha R.
    Latif, Aishah
    Chidiac, Omar M.
    Atkin, Stephen L.
    Abi Khalil, Charbel
    BMC ENDOCRINE DISORDERS, 2020, 20 (01)
  • [25] Seasonal Variation in Vitamin D3 Levels Is Paralleled by Changes in the Peripheral Blood Human T Cell Compartment
    Khoo, Ai-Leng
    Koenen, Hans J. P. M.
    Chai, Louis Y. A.
    Sweep, Fred C. G. J.
    Netea, Mihai G.
    van der Ven, Andre J. A. M.
    Joosten, Irma
    PLOS ONE, 2012, 7 (01):
  • [26] Low Levels of Serum Vitamin D3 Are Associated with Autoimmune Thyroid Disease in Pre-Menopausal Women
    Choi, Yun Mi
    Kim, Won Gu
    Kim, Tae Yong
    Bae, Sung Jin
    Kim, Hong-Kyu
    Jang, Eun Kyung
    Jeon, Min Ji
    Han, Ji Min
    Lee, Seung Hun
    Baek, Jung Hwan
    Shong, Young Kee
    Kim, Won Bae
    THYROID, 2014, 24 (04) : 655 - 661
  • [27] Association between vitamin D3 levels and insulin resistance: a large sample cross-sectional study
    Xu, Zixin
    Gong, Rongpeng
    Luo, Gang
    Wang, Mingxiang
    Li, Da
    Chen, Yue
    Shen, Xiaofang
    Wei, Xiaoxing
    Feng, Niran
    Wang, Shuangquan
    SCIENTIFIC REPORTS, 2022, 12 (01)
  • [28] Effect of different doses of parenteral vitamin D3 on serum 25 (OH) D concentrations
    Hashemipour, S.
    Sarukhani, M. R.
    Zadeh, Asef S.
    Ghazi, A. A.
    Mehrtash, B.
    Yazdi, Ahmadian M. H.
    DARU-JOURNAL OF PHARMACEUTICAL SCIENCES, 2009, 17 : 26 - 29
  • [29] Effects of vitamin D3 and vitamin E on prednisolone-induced alterations of phagocyte function
    Shymanskyy, I. O.
    Lisakovska, O. O.
    Mazanova, A. O.
    Riasniy, V. M.
    Veliky, M. M.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2016, 20 (07) : 1379 - 1383
  • [30] Primary Vitamin D Target Genes Allow a Categorization of Possible Benefits of Vitamin D3 Supplementation
    Carlberg, Carsten
    Seuter, Sabine
    de Mello, Vanessa D. F.
    Schwab, Ursula
    Voutilainen, Sari
    Pulkki, Kari
    Nurmi, Tarja
    Virtanen, Jyrki
    Tuomainen, Tomi-Pekka
    Uusitupa, Matti
    PLOS ONE, 2013, 8 (07):