Network Physiology in Aging and Frailty: The Grand Challenge of Physiological Reserve in Older Adults

被引:26
作者
Romero-Ortuno, Roman [1 ,2 ,3 ]
Martinez-Velilla, Nicolas [4 ]
Sutton, Richard [5 ]
Ungar, Andrea [6 ,7 ]
Fedorowski, Artur [8 ,9 ]
Galvin, Rose [10 ]
Theou, Olga [11 ]
Davies, Andrew [12 ,13 ]
Reilly, Richard B. [1 ,14 ]
Claassen, Jurgen [15 ]
Kelly, Aine M. [16 ]
Ivanov, Plamen Ch. [17 ]
机构
[1] Trinity Coll Dublin, Sch Med, Discipline Med Gerontol, Dublin, Ireland
[2] St James Hosp, Mercers Inst Successful Ageing, Dublin, Ireland
[3] Global Brain Hlth Inst, Trinity Coll Dublin, Dublin, Ireland
[4] Publ Univ Navarra UPNA, Navarra Hlth Res Inst IdisNa, Navarrabiomed, Complejo Hosp Navarra CHN, Pamplona, Spain
[5] Natl Heart & Lung Inst, Imperial Coll London, Fac Med, Heart Sci, London, England
[6] Univ Florence, Geriatr Dept, Florence, Italy
[7] Azienda Osped Univ Careggi, Florence, Italy
[8] Lund Univ, Skane Univ Hosp, Dept Clin Sci, Malmo, Sweden
[9] Skane Univ Hosp, Dept Cardiol, Malmo, Sweden
[10] Univ Limerick, Hlth Res Inst, Ageing Res Ctr, Sch Allied Hlth, Limerick, Ireland
[11] Dalhousie Univ, Physiotherapy & Geriatr Med, Halifax, NS, Canada
[12] Univ Coll Dublin, Trinity Coll Dublin, Sch Med, Dublin, Ireland
[13] Our Ladys Hosp & Care Serv, Dublin, Ireland
[14] Trinity Coll Dublin, Trinity Ctr Biomed Engn, Dublin, Ireland
[15] Radboud Univ Nijmegen, Med Ctr, Dept Geriatr Med, Nijmegen, Netherlands
[16] Trinity Coll Dublin, Sch Med, Discipline Physiol, Dublin, Ireland
[17] Boston Univ, Keck Lab Network Physiol, Boston, MA USA
来源
FRONTIERS IN NETWORK PHYSIOLOGY | 2021年 / 1卷
基金
爱尔兰科学基金会;
关键词
aging frailty; network physiology; reserve; resilience; dynamic coupling; FUNCTIONAL RESERVE; FALLS; DYNAMICS; HEART; TIME; AGE;
D O I
10.3389/fnetp.2021.712430
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
[No abstract available]
引用
收藏
页数:6
相关论文
共 62 条
[51]   Network Physiology of Cortico-Muscular Interactions [J].
Rizzo, Rossella ;
Zhang, Xiyun ;
Wang, Jilin W. J. L. ;
Lombardi, Fabrizio ;
Ivanov, Plamen Ch .
FRONTIERS IN PHYSIOLOGY, 2020, 11
[52]   Fitness and frailty: opposite ends of a challenging continuum! Will the end of age discrimination make frailty assessments an imperative? [J].
Romero-Ortuno, Roman ;
O'Shea, Diarmuid .
AGE AND AGEING, 2013, 42 (03) :279-280
[53]   Orthostatic haemodynamics may be impaired in frailty [J].
Romero-Ortuno, Roman ;
Cogan, Lisa ;
O'Shea, Diarmuid ;
Lawlor, Brian A. ;
Kenny, Rose Anne .
AGE AND AGEING, 2011, 40 (05) :576-583
[54]   Unifying aging and frailty through complex dynamical networks [J].
Rutenberg, Andrew D. ;
Mitnitski, Arnold B. ;
Farrell, Spencer G. ;
Rockwood, Kenneth .
EXPERIMENTAL GERONTOLOGY, 2018, 107 :126-129
[55]   What Is the Impact of Physical Activity and Physical Function on the Development of Multimorbidity in Older Adults Over Time? A Population-Based Cohort Study [J].
Ryan, Aine ;
Murphy, Catriona ;
Boland, Fiona ;
Galvin, Rose ;
Smith, Susan M. .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2018, 73 (11) :1538-1544
[56]   Fractal scale-invariant and nonlinear properties of cardiac dynamics remain stable with advanced age: a new mechanistic picture of cardiac control in healthy elderly [J].
Schmitt, Daniel T. ;
Ivanov, Plamen Ch. .
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2007, 293 (05) :R1923-R1937
[57]   Stratification Pattern of Static and Scale-Invariant Dynamic Measures of Heartbeat Fluctuations Across Sleep Stages in Young and Elderly [J].
Schmitt, Daniel T. ;
Stein, Phyllis K. ;
Ivanov, Plamen Ch. .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2009, 56 (05) :1564-1573
[58]   Event related potential and response time give evidence for a physiological reserve in cognitive functioning in relapsing-remitting multiple sclerosis [J].
Sundgren, Mathias ;
Wahlin, Ake ;
Maurex, Liselotte ;
Brismar, Tom .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2015, 356 (1-2) :107-112
[59]   Tilt testing remains a valuable asset [J].
Sutton, Richard ;
Fedorowski, Artur ;
Olshansky, Brian ;
van Dijk, J. Gert ;
Abe, Haruhiko ;
Brignole, Michele ;
de Lange, Frederik ;
Kenny, Rose Anne ;
Lim, Phang Boon ;
Moya, Angel ;
Rosen, Stuart D. ;
Russo, Vincenzo ;
Stewart, Julian M. ;
Thijs, Roland D. ;
Benditt, David G. .
EUROPEAN HEART JOURNAL, 2021, 42 (17) :1654-1660
[60]  
Tordi N., 2010, Annals of Physical and Rehabilitation Medicine, V53, P474, DOI 10.1016/j.rehab.2010.07.006