Network Physiology in Aging and Frailty: The Grand Challenge of Physiological Reserve in Older Adults

被引：31

作者：

Romero-Ortuno, Roman ^{[1
,2
,3
]}

Martinez-Velilla, Nicolas ^{[4
]}

Sutton, Richard ^{[5
]}

Ungar, Andrea ^{[6
,7
]}

Fedorowski, Artur ^{[8
,9
]}

Galvin, Rose ^{[10
]}

Theou, Olga ^{[11
]}

Davies, Andrew ^{[12
,13
]}

Reilly, Richard B. ^{[1
,14
]}

Claassen, Jurgen ^{[15
]}

Kelly, Aine M. ^{[16
]}

Ivanov, Plamen Ch. ^{[17
]}

机构：

[1] Trinity Coll Dublin, Sch Med, Discipline Med Gerontol, Dublin, Ireland

[2] St James Hosp, Mercers Inst Successful Ageing, Dublin, Ireland

[3] Global Brain Hlth Inst, Trinity Coll Dublin, Dublin, Ireland

[4] Publ Univ Navarra UPNA, Navarra Hlth Res Inst IdisNa, Navarrabiomed, Complejo Hosp Navarra CHN, Pamplona, Spain

[5] Natl Heart & Lung Inst, Imperial Coll London, Fac Med, Heart Sci, London, England

[6] Univ Florence, Geriatr Dept, Florence, Italy

[7] Azienda Osped Univ Careggi, Florence, Italy

[8] Lund Univ, Skane Univ Hosp, Dept Clin Sci, Malmo, Sweden

[9] Skane Univ Hosp, Dept Cardiol, Malmo, Sweden

[10] Univ Limerick, Hlth Res Inst, Ageing Res Ctr, Sch Allied Hlth, Limerick, Ireland

[11] Dalhousie Univ, Physiotherapy & Geriatr Med, Halifax, NS, Canada

[12] Univ Coll Dublin, Trinity Coll Dublin, Sch Med, Dublin, Ireland

[13] Our Ladys Hosp & Care Serv, Dublin, Ireland

[14] Trinity Coll Dublin, Trinity Ctr Biomed Engn, Dublin, Ireland

[15] Radboud Univ Nijmegen, Med Ctr, Dept Geriatr Med, Nijmegen, Netherlands

[16] Trinity Coll Dublin, Sch Med, Discipline Physiol, Dublin, Ireland

[17] Boston Univ, Keck Lab Network Physiol, Boston, MA USA

来源：

FRONTIERS IN NETWORK PHYSIOLOGY | 2021年 / 1卷

基金：

爱尔兰科学基金会;

关键词：

aging frailty; network physiology; reserve; resilience; dynamic coupling; FUNCTIONAL RESERVE; FALLS; DYNAMICS; HEART; TIME; AGE;

D O I：

10.3389/fnetp.2021.712430

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

[No abstract available]

引用

页数：6

共 62 条

[11] Atrial Fibrillation in Older Patients with Syncope and Dementia: Insights from the Syncope and Dementia Registry [J].

Ceccofiglio, Alice ;

Fumagalli, Stefano ;

Mussi, Chiara ;

Mossello, Enrico ;

Bo, Mario ;

Martone, Anna Maria ;

Bellelli, Giuseppe ;

Nicosia, Franco ;

Riccio, Daniela ;

Langellotto, Assunta ;

Tava, Gianni ;

Boccardi, Virginia ;

Tonon, Elisabetta ;

Abete, Pasquale ;

Ungar, Andrea .

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2020, 21 (09) :1238-1242

[12] Evidence for the Domains Supporting the Construct of Intrinsic Capacity [J].

Cesari, Matteo ;

de Carvalho, Islene Araujo ;

Thiyagarajan, Jotheeswaran Amuthavalli ;

Cooper, Cyrus ;

Martin, Finbarr C. ;

Reginster, Jean-Yves ;

Vellas, Bruno ;

Beard, John R. .

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2018, 73 (12) :1653-1660

[13] Sarcopenia and Neuroscience: Learning to Communicate [J].

Clark, Brian C. ;

Carson, Richard G. .

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2021, 76 (10) :1882-1890

[14] Physiological cardiac reserve: development of a non-invasive method and first estimates in man [J].

Cooke, GA ;

Marshall, P ;

Al-Timman, JK ;

Wright, DJ ;

Riley, R ;

Hainsworth, R ;

Tan, LB .

HEART, 1998, 79 (03) :289-294

[15] Observational study of sleep disturbances in advanced cancer [J].

Davies, Andrew Neil ;

Patel, Shuchita D. ;

Gregory, Amanda ;

Lee, Bernadette .

BMJ SUPPORTIVE & PALLIATIVE CARE, 2017, 7 (04) :435-440

[16] Orthostatic Blood Pressure Recovery Is Associated With the Rate of Cognitive Decline and Mortality in Clinical Alzheimer's Disease [J].

de Heus, Rianne A. A. ;

de Jong, Daan L. K. ;

Rijpma, Anne ;

Lawlor, Brian A. ;

Rikkert, Marcel G. M. Olde ;

Claassen, Jurgen A. H. R. .

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2020, 75 (11) :2169-2176

[17] Acute high-intensity aerobic exercise affects brain-derived neurotrophic factor in mild cognitive impairment: a randomised controlled study [J].

Devenney, Kate E. ;

Guinan, Emer M. ;

Kelly, Aine M. ;

Mota, Bibiana C. ;

Walsh, Cathal ;

Rikkert, Marcel Olde ;

Schneider, Stefan ;

Lawlor, Brian .

BMJ OPEN SPORT & EXERCISE MEDICINE, 2019, 5 (01)

[18]

Etzelmueller MS, 2020, IEEE ENG MED BIO, P5176, DOI 10.1109/EMBC44109.2020.9175672

[19] The potential for complex computational models of aging [J].

Farrell, Spencer ;

Stubbings, Garrett ;

Rockwood, Kenneth ;

Mitnitski, Arnold ;

Rutenberg, Andrew .

MECHANISMS OF AGEING AND DEVELOPMENT, 2021, 193

[20] Probing the network structure of health deficits in human aging [J].

Farrell, Spencer G. ;

Mitnitski, Arnold B. ;

Theou, Olga ;

Rockwood, Kenneth ;

Rutenberg, Andrew D. .

PHYSICAL REVIEW E, 2018, 98 (03)

← 1 2 3 4 5 6 7 →