Staphylococcus aureus Infections and Human Intestinal Microbiota

被引:16
作者
Liu, Aotong [1 ]
Garrett, Shari [2 ,3 ]
Hong, Wanqing [4 ,5 ]
Zhang, Jilei [1 ]
机构
[1] Univ Illinois, Coll Med, Dept Pharmacol & Regenerat Med, Chicago, IL 60612 USA
[2] Univ Illinois, Dept Med, Div Gastroenterol & Hepatol, Chicago, IL 60612 USA
[3] Univ Illinois, Dept Microbiol & Immunol, Chicago, IL 60612 USA
[4] Univ Waterloo, Fac Sci, Waterloo, ON N2L 3G1, Canada
[5] Shandong Normal Univ, Sch Chem & Chem Engn & Mat Sci, Jinan 250014, Peoples R China
来源
PATHOGENS | 2024年 / 13卷 / 04期
关键词
Staphylococcus aureus; bacterial translocation; gut microbiome; microbial homeostasis; dysbiosis; SOFT-TISSUE INFECTIONS; ENTEROTOXIN-B; EPIDEMIOLOGIC CHARACTERIZATION; CD1D-INDEPENDENT ACTIVATION; GUT MICROBIOTA; T-CELLS; ENDOCARDITIS; SKIN; BINDING; TRENDS;
D O I
10.3390/pathogens13040276
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Staphylococcus aureus (S. aureus) is a common pathogen that can cause many human diseases, such as skin infection, food poisoning, endocarditis, and sepsis. These diseases can be minor infections or life-threatening, requiring complex medical management resulting in substantial healthcare costs. Meanwhile, as the critically ignored "organ," the intestinal microbiome greatly impacts physiological health, not only in gastrointestinal diseases but also in disorders beyond the gut. However, the correlation between S. aureus infection and intestinal microbial homeostasis is largely unknown. Here, we summarized the recent progress in understanding S. aureus infections and their interactions with the microbiome in the intestine. These summarizations will help us understand the mechanisms behind these infections and crosstalk and the challenges we are facing now, which could contribute to preventing S. aureus infections, effective treatment investigation, and vaccine development.
引用
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页数:16
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共 130 条
  • [121] mecA gene is widely disseminated in Staphylococcus aureus population
    Wielders, CLC
    Fluit, AC
    Brisse, S
    Verhoef, J
    Schmitz, FJ
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (11) : 3970 - 3975
  • [122] Trends in sources of meticillin-resistant Staphylococcus aureus (MRSA) bacteraemia: data from the national mandatory surveillance of MRSA bacteraemia in England, 2006-2009
    Wilson, J.
    Guy, R.
    Elgohari, S.
    Sheridan, E.
    Davies, J.
    Lamagni, T.
    Pearson, A.
    [J]. JOURNAL OF HOSPITAL INFECTION, 2011, 79 (03) : 211 - 217
  • [123] Molecular characterization of Staphylococcus aureus isolates causing skin and soft tissue infections (SSTIs)
    Yao, Dan
    Yu, Fang-you
    Qin, Zhi-qiang
    Chen, Chun
    He, Su-su
    Chen, Zeng-qiang
    Zhang, Xue-qing
    Wang, Liang-xing
    [J]. BMC INFECTIOUS DISEASES, 2010, 10
  • [124] Epidemiology of Community-Onset Staphylococcus aureus Bacteremia
    Yarovoy, James Y.
    Monte, Andrew A.
    Knepper, Bryan C.
    Young, Heather L.
    [J]. WESTERN JOURNAL OF EMERGENCY MEDICINE, 2019, 20 (03) : 438 - 442
  • [125] The Role of Regulatory Mechanisms and Environmental Parameters in Staphylococcal Food Poisoning and Resulting Challenges to Risk Assessment
    Zeaki, Nikoleta
    Johler, Sophia
    Skandamis, Panagiotis N.
    Schelin, Jenny
    [J]. FRONTIERS IN MICROBIOLOGY, 2019, 10
  • [126] Imbalance of the intestinal virome and altered viral-bacterial interactions caused by a conditional deletion of the vitamin D receptor
    Zhang, Jilei
    Zhang, Yongguo
    Xia, Yinglin
    Sun, Jun
    [J]. GUT MICROBES, 2021, 13 (01)
  • [127] Breast and gut microbiome in health and cancer
    Zhang, Jilei
    Xia, Yinglin
    Sun, Jun
    [J]. GENES & DISEASES, 2021, 8 (05) : 581 - 589
  • [128] Apoptosis induced by Staphylococcus aureus toxins
    Zhang, Xiaopeng
    Hu, Xiaomei
    Rao, Xiancai
    [J]. MICROBIOLOGICAL RESEARCH, 2017, 205 : 19 - 24
  • [129] Gut microbiota-mediated secondary bile acid alleviates Staphylococcus aureus-induced mastitis through the TGR5-cAMP-PKA-NF-κB/NLRP3 pathways in mice
    Zhao, Caijun
    Wu, Keyi
    Hao, Haoyang
    Zhao, Yihong
    Bao, Lijuan
    Qiu, Min
    He, Yuhong
    He, Zhaoqi
    Zhang, Naisheng
    Hu, Xiaoyu
    Fu, Yunhe
    [J]. NPJ BIOFILMS AND MICROBIOMES, 2023, 9 (01)
  • [130] Transcytosis, Antitumor Activity and Toxicity of Staphylococcal Enterotoxin C2 as an Oral Administration Protein Drug
    Zhao, Wenbin
    Li, Yangyang
    Liu, Wenhui
    Ding, Ding
    Xu, Yingchun
    Pan, Liqiang
    Chen, Shuqing
    [J]. TOXINS, 2016, 8 (06):