Preparation and characterization of soluble hemostatic medical cotton gauze

被引：0
|
作者：
Qian L. [1 ]
Zhang B. [1 ,2 ]
机构：
[1] College of Textiles, Donghua University, Shanghai
[2] Key Laboratory of Textile Science and Technology, Ministry of Education, Donghua University, Shanghai
来源：
Fangzhi Xuebao/Journal of Textile Research | 2019年 / 40卷 / 05期
关键词：
Carboxymethylation; Medical gauze; Solubility; Solvent medium method;
D O I：
10.13475/j.fzxb.20180500905
中图分类号：
学科分类号：
摘要：
In order to improve the solubility of carboxymethyl medical cotton gauze to achieve good hemostatic effect, single factor analytical method was adopted to investigate the process conditions of solvent medium method. The influence of the mass fraction of sodium hydroxide and time of alkalization pre-treatment, the mass fraction of chloroacetic acid, temperature and time of etherification reaction on the solubility of cotton gauze were studied. The optimum preparation processes were obtained and the soluble hemostatic gauzes were characterized by Fourier transform infrared spectrometer and scanning electronic microscopy. The results show that the optimum soluble hemostatic gauzes are produced under the condition of 20% mass fraction of sodium hydroxide and alkalization pre-treatment for 30 min, 10.5% mass fraction of chloroacetic acid, etherification at 70℃ for 4 h, while the dissolution time is 4 h. The cotton gauze is carboxymethylated, and the diameters of fibers increase after carboxymethylation. Copyright No content may be reproduced or abridged without authorization.
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页码：102 / 106
页数：4
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