Advances in the development of Artificial Hearts in the Department of Energy and Power Engineering of Tsinghua University

被引：0

作者：

Huang B. ^{[1
]}

Li H. ^{[1
]}

Lu B. ^{[2
]}

Zuo Z. ^{[1
]}

Luo X. ^{[1
]}

Liu S. ^{[1
]}

机构：

[1] Department of Energy and Power Engineering, Tsinghua University, Beijing

[2] Zhejiang Qingke Pumping Medical Technology Limited, Taizhou

来源：

Qinghua Daxue Xuebao/Journal of Tsinghua University | 2022年 / 62卷 / 04期

关键词：

Artificial Hearts; Centrifugal pumps; Hemolysis; Hydrodynamics;

D O I：

10.16511/j.cnki.qhdxxb.2022.25.030

中图分类号：

学科分类号：

摘要：

The latest generation of Artificial Hearts are using centrifugal blood pumps to provide important support for patients with cardiovascular diseases. This paper describes the advances in the development of Artificial Hearts in the Department of Energy and Power Engineering of Tsinghua University. A pump design optimization method was proposed based on the maximum scalar shear stress for the hemolysis standard to raduce the calculational load and improve the optimization efficiency. A blood-cell-damage model based on the turbulent viscous dissipative stress was developed for better prediction. Both extracorporeal pumps with bearings and left ventricular assist device (LVAD) prototypes with magneto-hydraulic suspensions have been developed with studies of their hydraulics. Model predictions agree with the experimental data with an error of 3.6%. A medical fluid flow experimental system has been developed to improve research on Artificial Heart prototypes through evaluations of the physiological effects of new Artificial Heart designs. © 2022, Tsinghua University Press. All right reserved.

引用

页码：746 / 757

页数：11

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