A comparative study on myomectomy and total hysterectomy in the treatment of perimenopausal uterine fibroids

This study aims to compare the clinical efficacy of myomectomy and total hysterectomy in the treatment of perimenopausal uterine fibroids. 124 cases of uterine fibroids were randomly divided into a control group and a study group, each with 62 cases. The control group underwent a total hysterectomy. Study participants underwent a myomectomy. Both groups of patients were observed and compared for surgery-related indicators, quality of life scores, perimenopausal syndrome and inflammatory factors. The study group had a shorter operation time and less intraoperative blood loss (p < 0.05). Before operation, there was no significant difference in Quality of life Short Form 36 (SF-36) score, Interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha) and IL-10 between both groups (p > 0.05) at 6 months after operation, SF-36 score in both groups were higher than before operation, and IL-6, TNF-alpha and IL-10 in both groups were higher than before operation (p < 0.05). Perimenopausal syndrome incidence was significantly lower in the study group than in the control group (p < 0.05). Myomectomy is more suitable for treating perimenopausal uterine fibroids.