Exceptional Response to Bromodomain and Extraterminal Domain Inhibitor Therapy With BMS-986158 in BRD4-NUTM1 NUT Carcinoma Harboring a BRD4 Splice Site Mutation

被引:3
作者
Cheng, Michael L. [1 ,2 ]
Huang, Yeying [3 ]
Luong, Nhi [3 ]
LoPiccolo, Jaclyn [1 ,2 ]
Nishino, Mizuki [4 ,5 ]
Sholl, Lynette M. [3 ]
Chirieac, Lucian R. [3 ]
Santucci, Alison D. [1 ,6 ]
Rabin, Michael S. [1 ,2 ]
Jaenne, Pasi A. [1 ,2 ]
Coker, Shodeinde [7 ]
Diamond, Jennifer R. [8 ]
Hilton, John [9 ]
Shapiro, Geoffrey I. [2 ]
French, Christopher A. [3 ,10 ]
机构
[1] Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA USA
[2] Harvard Med Sch, Dana Farber Canc Inst, Med Oncol, Boston, MA 02115 USA
[3] Harvard Med Sch, Brigham & Womens Hosp, Dept Pathol, Boston, MA USA
[4] Brigham & Womens Hosp, Harvard Med Sch, Dept Radiol, Boston, MA USA
[5] Harvard Med Sch, Dana Farber Canc Inst, Dept Imaging, Boston, MA 02115 USA
[6] Boston Med Ctr, Boston, MA USA
[7] Bristol Myers Squibb, Lawrenceville, NJ USA
[8] Univ Colorado, Canc Ctr, Aurora, CO USA
[9] Ottawa Hosp, Div Med Oncol, Ottawa, ON, Canada
[10] Harvard Med Sch, Brigham & Womens Hosp, Dept Pathol, 77 Ave Louis Pasteur, Boston, MA 02115 USA
基金
美国国家卫生研究院;
关键词
PROTEIN; ONCOPROTEIN; CHROMATIN;
D O I
10.1200/PO.22.00633
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页数:7
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