Small extracellular vesicles are rejuvenating factors in young blood

被引：1
|
作者：
Chen, Xi [1 ]
Luo, Yang [1 ]
机构：
[1] Nanjing Univ, Nanjing, Jiangsu, Peoples R China
来源：
NATURE AGING | 2024年 / 4卷 / 06期
关键词：
D O I：
10.1038/s43587-024-00650-y
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Small extracellular vesicles (sEVs) derived from the blood of young mice are shown to have the potential to extend lifespan and rejuvenate physiological functions in aged mice. Mechanistically, microRNA (miRNA) cargoes within these sEVs alleviated age-related dysfunction by promoting the expression of PGC1 alpha and enhancing mitochondrial energy metabolism.
引用
收藏
页码：759 / 760
页数：2
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