Knowledge and attitude regarding rotavirus and its vaccination among medical students in Karachi, Pakistan

Objective: The aim of this study is to determine the knowledge and attitude regarding rotavirus and its vaccination among medical students. Study design: It is a cross sectional study. Methods: Total 324 medical students were selected through stratified random sampling. A structured and validated questionnaire was used. Knowledge and attitude were recorded on scale. Independent t-test and ANVOA was used to determine the difference among gender and academic year. Regression and correlation analysis was done to determine the correlation of knowledge and attitude level with age and academic year of study. p value <= 0.05 considered as statistically significant. Results: Mean and standard deviation score of students were 7.88 +/- 2.46 on knowledge scale and 4.16 +/- 1.23 on attitude scale. Total 87% of students were aware of rotavirus and its vaccination. Both knowledge and attitude level were increased significantly with increasing year of study and age. After adjustment of covariate, Age and academic year of study were the significant factors in determining the scores on knowledge scale. (beta coefficient 0.056 with p-value 0.003 and 0.433 with p-value-0.000). Conclusion: Medical students were appropriate knowledge about the rotavirus but attitude toward rotavirus vaccination is unsatisfactory. It should be a part of the curriculum of not just medical students but all students from high school to undergrad level regardless of the course they are enrolled in and also be advertised by the government.