Lysosomal cystine accumulation activates mTOR signaling in cystinosis: are mTOR inhibitors the cure?

被引:0
作者
Christer, Saloemon [1 ]
Simons, Matias [1 ]
机构
[1] Univ Hosp Heidelberg, Inst Human Genet, Nephrogenet Unit, Neuenheimer Feld 366, D-69120 Heidelberg, Germany
关键词
cystine; Fanconi syndrome; lysosomes; proximal tubular cells; mTOR signaling;
D O I
10.1016/j.kint.2023.11.030
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:656 / 658
页数:3
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