Exploring the potential of 3D and 4D printing in advancing stent manufacturing for cardiovascular diseases

被引:9
作者
Hatami, Hooman [1 ]
Almahmeed, Wael [2 ]
Kesharwani, Prashant [3 ]
Sahebkar, Amirhossein [4 ,5 ,6 ]
机构
[1] Mashhad Univ Med Sci, Sch Pharm, Dept Pharmaceut, Mashhad, Iran
[2] Cleveland Clin Abu Dhabi, Heart & Vasc Inst, Abu Dhabi, U Arab Emirates
[3] Jamia Hamdard, Sch Pharmaceut Educ & Res, Dept Pharmaceut, New Delhi 110062, India
[4] Saveetha Univ, Saveetha Med Coll & Hosp, Saveetha Inst Med & Tech Sci, Ctr Global Hlth Res, Chennai, India
[5] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Biotechnol Res Ctr, Mashhad, Iran
[6] Mashhad Univ Med Sci, Appl Biomed Res Ctr, Mashhad, Iran
基金
俄罗斯科学基金会;
关键词
Cardiovascular diseases; Polymers; Stents; 3D printing; 4D printing; Technology; ELUTING STENT; LIFE-STYLE; MEMORY; THROMBOSIS; ANTIBACTERIAL; FABRICATION; FATIGUE; STATINS; DESIGN;
D O I
10.1016/j.eurpolymj.2024.113035
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide. While the application of vascular stents has significantly improved the management of atherothrombotic events, there are still drawbacks and challenges that need addressing. Restenosis and thrombosis present significant risks related to stent usage, and certain patient populations may require additional treatment or monitoring. Hence, novel stent designs and technologies are being explored aimed at overcoming these limitations and enhancing outcomes for patients. One emerging approach involves using 3D and 4D printing to manufacture stents. Stents produced with these methods are more beneficial, tailored to individuals, and less invasive than traditional manufacturing approaches. While conventional techniques rely on subtracting material from a block to achieve a shape, 3D and 4D printing utilize additive processes to build objects layer by layer. These technologies offer many benefits versus traditional methods, like improved customization abilities, complex geometries, and biocompatibility. These benefits lead to enhanced outcomes and reduced complications in addition to shorter procedures and lower costs. This article aims to examine this technology and explore its potential advantages and drawbacks for the management of CVDs.
引用
收藏
页数:11
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