Management of advanced prostate cancer in the Asia-Pacific region: Summary of the Asia-Pacific Advanced Prostate Cancer Consensus Conference 2023

被引：1

作者：

Chiong, Edmund ^{[1
,2
]}

Murphy, Declan G. ^{[2
]}

Buchan, Nicholas ^{[3
,4
,5
]}

Chen, Kenneth ^{[6
]}

Chen, Sarah S. ^{[7
]}

Chua, Melvin L. K. ^{[8
]}

Hamid, Agus Rizal ^{[9
]}

Kanesvaran, Ravindran ^{[10
]}

Khochikar, Makarand ^{[11
]}

Letran, Jason ^{[12
]}

Lojanapiwat, Bannakij ^{[13
]}

Mallik, Indranil ^{[14
]}

Ng, Chee Fai ^{[15
]}

Ong, Teng Aik ^{[16
]}

Poon, Darren M. C. ^{[17
]}

Pu, Yeong-Shiau ^{[18
]}

Saad, Marniza ^{[19
]}

Schubach, Kathryn ^{[4
,5
,20
]}

Takahara, Kiyoshi ^{[21
]}

Tey, Jeremy ^{[22
]}

Thang, Sue-Ping ^{[23
]}

Toh, Poh Choo ^{[1
,2
]}

Turkeri, Levent ^{[23
]}

Vinh, Nguyen Tuan ^{[24
]}

Williams, Scott ^{[4
,5
,25
]}

Ye, Dingwei ^{[26
]}

Davis, Ian D. ^{[27
,28
]}

机构：

[1] Natl Univ Singapore Hosp, Dept Urol, Singapore, Singapore

[2] Natl Univ Singapore, Dept Surg, Singapore, Singapore

[3] Christchurch Publ Hosp, Dept Urol, Christchurch, New Zealand

[4] Monash Univ, Melbourne, Vic, Australia

[5] Eastern Hlth, Melbourne, Vic, Australia

[6] Singapore Gen Hosp, Dept Urol, Singapore, Singapore

[7] Tan Tock Seng Hosp, Dept Nursing, Singapore, Singapore

[8] Natl Canc Ctr Singapore, Dept Head & Neck & Thorac Canc, Div Radiat Oncol, Singapore, Singapore

[9] Univ Indonesia, CiptoMangunkusumo Hosp, Fac Med, Dept Urol, Jakarta, Indonesia

[10] Natl Canc Ctr Singapore, Div Med Oncol, Singapore, Singapore

[11] Amrita Inst Med Sci, Dept Urol Urooncol, Ponekkara, Kerala, India

[12] Chinese Gen Hosp & Med Ctr, Dept Urol, Manila, Philippines

[13] Chiang Mai Univ, Dept Surg, Chiang Mai, Thailand

[14] Tata Med Ctr, Dept Radiat Oncol, Kolkata, India

[15] Chinese Univ Hong Kong, SH Ho Urol Ctr, Hong Kong, Peoples R China

[16] Univ Malaya, Dept Surg, Kuala Lumpur, Malaysia

[17] Chinese Univ Hong Kong, Dept Clin Oncol, Hong Kong, Peoples R China

[18] Natl Taiwan Univ, Coll Med & Hosp, Dept Urol, Taipei, Taiwan

[19] Univ Malaya, Fac Med, Dept Clin Oncol, Kuala Lumpur, Malaysia

[20] Australian & New Zealand Urol Nurses ANZUNS, Melbourne, Vic, Australia

[21] Fujita Hlth Univ, Dept Urol, Toyoake, Aichi, Japan

[22] Natl Univ Canc Inst, Dept Radiat Oncol, Singapore, Singapore

[23] Singapore Gen Hosp, Dept Nucl Med & Mol Imaging, Singapore, Singapore

[24] Binh Dan Hosp, Dept Urol, Ho Chi Minh City, Vietnam

[25] Peter MacCallum Canc Ctr, Dept Radiat Oncol, Melbourne, Vic, Australia

[26] Fudan Univ, Shanghai Canc Ctr, Shanghai, Peoples R China

[27] Lifehouse, Camperdown, NSW, Australia

[28] Level 2,5 Arnold St, Box Hill, Vic 3128, Australia

来源：

ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY | 2024年 / 20卷 / 04期

关键词：

Asia-Pacific; consensus; guideline; metastasis; prostate cancer; POST-HOC ANALYSIS; RADIOGRAPHIC PROGRESSION; MEN; ANTIGEN; PSA; ENZALUTAMIDE; THERAPY; RISK;

D O I：

10.1111/ajco.14064

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

AimThe aim of the third Asia-Pacific Advanced Prostate Cancer Consensus Conference (APAC APCCC 2023) was to discuss the application in the Asia-Pacific (APAC) region of consensus statements from the 4th Advanced Prostate Cancer Consensus Conference (APCCC 2022).MethodsThe one-day meeting in July 2023 brought together 27 experts from 14 APAC countries. The meeting covered five topics: (1) Intermediate- and high-risk and locally advanced prostate cancer; (2) Management of newly diagnosed metastatic hormone-sensitive prostate cancer; (3) Management of non-metastatic castration-resistant prostate cancer; (4) Homologous recombination repair mutation testing; (5) Management of metastatic castration-resistant prostate cancer. Pre- and post-symposium polling gathered APAC-specific responses to APCCC consensus questions and insights on current practices and challenges in the APAC region.ResultsAPAC APCCC highlights APAC-specific considerations in an evolving landscape of diagnostic technologies and treatment innovations for advanced prostate cancer. While new technologies are available in the region, cost and reimbursement continue to influence practice significantly. Individual patient considerations, including the impact of chemophobia on Asian patients, also influence decision-making.ConclusionThe use of next-generation imaging, genetic testing, and new treatment combinations is increasing the complexity and duration of prostate cancer management. Familiarity with new diagnostic and treatment options is growing in the APAC region. Insights highlight the continued importance of a multidisciplinary approach that includes nuclear medicine, genetic counseling, and quality-of-life expertise. The APAC APCCC meeting provides an important opportunity to share practice and identify APAC-specific issues and considerations in areas of low evidence where clinical experience is growing. Structure, attendees, discussion topics, and key themes of Asia Pacific Advanced Prostate Cancer Consensus Conference 2023. image

引用

页码：481 / 490

页数：10

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