Scientific techniques in adolescent and young adult classic Hodgkin lymphoma

被引:0
|
作者
Maura, Francesco [1 ]
Adams, Ragini M. [2 ]
Aoki, Tomohiro [3 ,4 ]
机构
[1] Univ Miami, Sylvester Comprehens Canc Ctr, Miami, FL USA
[2] Stanford Univ, Div Pediat Hematol Oncol, Sch Med, Stanford, CA USA
[3] Univ Hlth Network, Princess Margaret Canc Ctr, Toronto, ON, Canada
[4] Univ Hlth Network, Princess Margaret Canc Ctr, 700 Univ Ave,6th Floor Workstat 6W472, Toronto, ON M5G 1Z5, Canada
来源
EJHAEM | 2023年 / 4卷 / 04期
关键词
MUTATIONAL EVOLUTION; TUMOR; GENOME; REED; EXPRESSION; NIVOLUMAB; BLOCKADE; DISEASE; REVEAL; PD-L1;
D O I
10.1002/jha2.786
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Understanding the tumor microenvironment and genomic landscape is crucial for better prediction of treatment outcomes and developing novel therapies in Hodgkin lymphoma (HL). Recent advancements in genomics have enabled researchers to gain deeper insights into the genomic characteristics of HL at both single-cell resolution and the whole genome level. The use of noninvasive methods such as liquid biopsies and formalin-fixed paraffin-embedded-based imaging techniques has expanded the possibilities of applying cutting-edge analyses to routine clinically available samples. Collaborative efforts between adult and pediatric group are imperative to translate novel findings into routine patient care. image
引用
收藏
页码:902 / 907
页数:6
相关论文
共 50 条
  • [31] A significant proportion of classic Hodgkin lymphoma recurrences represents clonally unrelated second primary lymphoma
    van Bladel, Diede A. G.
    Stevens, Wendy B. C.
    Kroeze, Leonie I.
    de Groen, Ruben A. L.
    de Groot, Fleur A.
    van der Last-Kempkes, Jessica L. M.
    Berendsen, Madeleine R.
    Rijntjes, Jos
    Luijks, Jeroen A. C. W.
    Bonzheim, Irina
    van der Spek, Ellen
    Plattel, Wouter J.
    Pruijt, Johannes F. M.
    de Jonge-Peeters, Susan D. P. W. M.
    Velders, Gerjo A.
    Lensen, Chantal
    van Bladel, Esther R.
    Fdermann, Birgit
    Hoevenaars, Birgit M.
    Pastorczak, Agata
    ten Bosch, Jutte van der Werff
    Vermaat, Joost S. P.
    Nooijen, Peet T. G. A.
    Hebeda, Konnie M.
    Fend, Falko
    Diepstra, Arjan
    van Krieken, J. Han J. M.
    Groenen, Patricia J. T. A.
    van den Brand, Michiel
    Scheijen, Blanca
    BLOOD ADVANCES, 2023, 7 (19) : 5911 - 5924
  • [32] Adolescent Hodgkin Lymphoma: Are Treatment Results More Favorable With Pediatric Than With Adult Regimens?
    Mueller, Judit
    Illes, Arpad
    Molnar, Zsuzsanna
    Rosta, Andras
    Varoczy, Laszlo
    Kovacs, Gabor
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2011, 33 (02) : E60 - E63
  • [33] The composite lymphoma: chronic lymphocytic leukemia - classic Hodgkin's lymphoma
    Badea, M.
    Dobrea, Camelia
    Badea, Daniela
    Genunche-Dumitrescu, Amelia
    Mitrut, P.
    Duta, Doriana
    ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY, 2010, 51 (02): : 353 - 358
  • [34] Optimizing checkpoint inhibitors therapy for relapsed or progressive classic Hodgkin lymphoma by multiplex immunohistochemistry of the tumor microenvironment
    Carbone, Antonino
    Gloghini, Annunziata
    Pruneri, Giancarlo
    Dolcetti, Riccardo
    CANCER MEDICINE, 2019, 8 (06): : 3012 - 3016
  • [35] Diagnosis of classic Hodgkin lymphoma on bone marrow biopsy
    Laurent, Camille
    Arber, Daniel A.
    Johnston, Peter
    Fend, Falko
    Zamo, Alberto
    Attygalle, Ayoma D.
    HISTOPATHOLOGY, 2020, 76 (07) : 934 - 941
  • [36] Concurrent pembrolizumab with AVD for untreated classic Hodgkin lymphoma
    Lynch, Ryan C.
    Ujjani, Chaitra S.
    Poh, Christina
    Warren, Edus H.
    Smith, Stephen D.
    Shadman, Mazyar
    Till, Brian
    Raghunathan, Vikram M.
    Alig, Stefan
    Alizadeh, Ash A.
    Gulhane, Avanti
    Chen, Delphine L.
    Tseng, Yolanda
    Coye, Hilary
    Shelby, Megan
    Ottemiller, Susan
    Keo, Sarith
    Verni, Kaitlin
    Du, Hongyan
    Vandermeer, Jacquelin
    Gaston, Ashley
    Rasmussen, Heather
    Martin, Paul
    Marzbani, Edmond
    Voutsinas, Jenna
    Gopal, Ajay K.
    BLOOD, 2023, 141 (21) : 2576 - 2586
  • [37] Integrating Novel Agents into the Treatment of Classic Hodgkin Lymphoma
    LaCasce, Ann S.
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2021, 21 : S166 - S167
  • [38] Composite Lymphoma: EBV-positive Classic Hodgkin Lymphoma and Peripheral T-cell Lymphoma A Case Report
    Gualco, Gabriela
    Chioato, Lucimara
    Van Den Berg, Anke
    Weiss, Lawrence M.
    Bacchi, Carlos E.
    APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2009, 17 (01) : 72 - 76
  • [39] Classic Hodgkin lymphoma in pelvis A case report highlights diagnosis and treatment challenges
    Tang, Fan
    Min, Li
    Ye, Yunxia
    Tang, Bo
    Zhou, Yong
    Zhang, Wenli
    Tu, Chongqi
    MEDICINE, 2017, 96 (39)
  • [40] Distinctive patterns of marrow involvement by classic Hodgkin lymphoma are clues for diagnosis and subtyping
    Li, Hsin-Ni
    Wang, Ren Ching
    Chen, Chuan-Han
    Chen, Jun-Peng
    Yang, Sheau-Fang
    Chen, Shang-Wen
    Chuang, Shih-Sung
    VIRCHOWS ARCHIV, 2022, 480 (04) : 899 - 907