Scientific techniques in adolescent and young adult classic Hodgkin lymphoma

被引:0
|
作者
Maura, Francesco [1 ]
Adams, Ragini M. [2 ]
Aoki, Tomohiro [3 ,4 ]
机构
[1] Univ Miami, Sylvester Comprehens Canc Ctr, Miami, FL USA
[2] Stanford Univ, Div Pediat Hematol Oncol, Sch Med, Stanford, CA USA
[3] Univ Hlth Network, Princess Margaret Canc Ctr, Toronto, ON, Canada
[4] Univ Hlth Network, Princess Margaret Canc Ctr, 700 Univ Ave,6th Floor Workstat 6W472, Toronto, ON M5G 1Z5, Canada
来源
EJHAEM | 2023年 / 4卷 / 04期
关键词
MUTATIONAL EVOLUTION; TUMOR; GENOME; REED; EXPRESSION; NIVOLUMAB; BLOCKADE; DISEASE; REVEAL; PD-L1;
D O I
10.1002/jha2.786
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Understanding the tumor microenvironment and genomic landscape is crucial for better prediction of treatment outcomes and developing novel therapies in Hodgkin lymphoma (HL). Recent advancements in genomics have enabled researchers to gain deeper insights into the genomic characteristics of HL at both single-cell resolution and the whole genome level. The use of noninvasive methods such as liquid biopsies and formalin-fixed paraffin-embedded-based imaging techniques has expanded the possibilities of applying cutting-edge analyses to routine clinically available samples. Collaborative efforts between adult and pediatric group are imperative to translate novel findings into routine patient care. image
引用
收藏
页码:902 / 907
页数:6
相关论文
共 50 条
  • [21] Autologous hematopoietic cell transplantation for the treatment of relapsed/refractory pediatric, adolescent, and young adult Hodgkin lymphoma: a single institutional experience
    Talleur, Aimee C.
    Flerlage, Jamie E.
    Shook, David R.
    Chilsen, Abigail M.
    Hudson, Melissa M.
    Cheng, Cheng
    Huang, Sujuan
    Triplett, Brandon M.
    BONE MARROW TRANSPLANTATION, 2020, 55 (07) : 1357 - 1366
  • [22] Radiation Therapy Use in Refractory and Relapsed Adolescent and Young Adult Hodgkin Lymphoma: A Report from the Children's Oncology Group
    Vega, Raymond B. Mailhot
    Harker-Murray, Paul D.
    Forlenza, Christopher J.
    Cole, Peter
    Kelly, Kara M.
    Milgrom, Sarah A.
    Parikh, Rahul R.
    Hodgson, David C.
    Castellino, Sharon M.
    Kahn, Justine
    Roberts, Kenneth B.
    Constine, Louis S.
    Hoppe, Bradford S.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2023, 117 (02): : 400 - 403
  • [23] PD-1/PD-L1 Pathway and Its Blockade in Patients with Classic Hodgkin Lymphoma and Non-Hodgkin Large-Cell Lymphomas
    Xie, Wei
    Medeiros, L. Jeffrey
    Li, Shaoying
    Yin, C. Cameron
    Khoury, Joseph D.
    Xu, Jie
    CURRENT HEMATOLOGIC MALIGNANCY REPORTS, 2020, 15 (04) : 372 - 381
  • [24] Clinicopathological significance of CD79a expression in classic Hodgkin lymphoma
    Sakatani, Akio
    Igawa, Takuro
    Okatani, Takeshi
    Fujihara, Megumu
    Asaoku, Hideki
    Sato, Yasuharu
    Yoshino, Tadashi
    JOURNAL OF CLINICAL AND EXPERIMENTAL HEMATOPATHOLOGY, 2020, 60 (03) : 78 - 86
  • [25] Follicular Helper T-cell Lymphoma With Hodgkin/Reed-Sternberg-Like Cells Versus Classic Hodgkin Lymphoma
    Petronilho, Sara
    Poullot, Elsa
    Andre, Axel
    Robe, Cyrielle
    Nouhoum, Sako
    Fataccioli, Virginie
    Quintela, Jose Miguel
    Claudel, Alexis
    Briere, Josette
    Lechapt, Emmanuele
    Lemonnier, Francois
    Henrique, Rui
    de Leval, Laurence
    Gaulard, Philippe
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2025, 49 (03) : 273 - 283
  • [26] GATA3 Immunohistochemical Staining in Hodgkin Lymphoma: Diagnostic Utility in Differentiating Classic Hodgkin Lymphoma From Nodular Lymphocyte Predominant Hodgkin Lymphoma and Other Mimicking Entities
    Kezlarian, Brie
    Alhyari, Mohammad
    Venkataraman, Girish
    Karner, Kristin
    Inamdar, Kedar V.
    Menon, Madhu P.
    APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2019, 27 (03) : 180 - 184
  • [27] Histology of pediatric classic Hodgkin lymphoma: From diagnosis to prognostic stratification
    Pizzi, Marco
    Tazzoli, Sara
    Carraro, Elisa
    Chaviano, Felicia
    Massano, Davide
    Lovisa, Federica
    Mussolin, Lara
    Todesco, Alessandra
    Biffi, Alessandra
    d'Amore, Emanuele S.
    Pillon, Marta
    Rugge, Massimo
    PEDIATRIC BLOOD & CANCER, 2020, 67 (05)
  • [28] Tumour Microenvironment Contribution to Checkpoint Inhibitor Therapy in Classic Hodgkin Lymphoma
    Gloghini, Annunziata
    Carbone, Antonino
    HEMATO, 2024, 5 (02): : 199 - 207
  • [29] Posttransplant Classic Hodgkin Lymphoma: Richter Transformation or Posttransplant Lymphoproliferative Disorder?
    Lee, Ina
    Zou, Ying
    Hodges, Susan
    Rapoport, Aaron P.
    Hardy, Nancy
    Singh, Zeba
    AJSP-REVIEWS AND REPORTS, 2019, 24 (05): : 212 - 217
  • [30] A protective role for early oral exposures in the etiology of young adult Hodgkin lymphoma
    Cozen, Wendy
    Hamilton, Ann S.
    Zhao, Peng
    Salam, Muhammad T.
    Deapen, Dennis M.
    Nathwani, Bharat N.
    Weiss, Lawrence M.
    Mack, Thomas M.
    BLOOD, 2009, 114 (19) : 4014 - 4020