Cause-Specific Excess Mortality During the COVID-19 Pandemic (2020-2021) in 12 Countries of the C-MOR Consortium

被引：4

作者：

Beeks, Victoria Virginia ^{[1
]}

Achilleos, Souzana ^{[1
]}

Quattrocchi, Annalisa ^{[1
]}

Pallari, Chryso Th. ^{[1
]}

Critselis, Elena ^{[1
]}

Salameh, Pascale ^{[1
]}

Haghighi, Mohammad Reza Rahmanian ^{[1
]}

Rodriguez-Llanes, Jose Manuel ^{[2
]}

Ambrosio, Giuseppe ^{[3
]}

Artemiou, Andreas ^{[4
]}

Gabel, John ^{[5
]}

Bennett, Catherine Marie ^{[6
]}

Cuthbertson, Joseph ^{[7
]}

Zimmermann, Claudia ^{[8
]}

Schernhammer, Eva Susanna ^{[8
]}

Costa, Antonio Jose Leal ^{[9
]}

de Carvalho, Luciana Freire ^{[9
]}

Lobato, Jackeline Christiane Pinto ^{[10
]}

Athanasiadou, Maria ^{[11
]}

Critchley, Julia Alison ^{[12
]}

Goldsmith, Lucy Pollyanna ^{[12
]}

Kandelaki, Levan ^{[13
]}

Glushkova, Natalya ^{[14
]}

Davletov, Kairat ^{[15
]}

Semenova, Yuliya ^{[16
]}

Erzen, Ivan ^{[17
]}

Verstiuk, Olesia ^{[18
]}

Alekkou, Dimos ^{[19
]}

Polemitis, Antonis ^{[20
]}

Charalambous, Andreas ^{[21
]}

Demetriou, Christiana A. ^{[1
]}

机构：

[1] Univ Nicosia, Med Sch, Dept Primary Care & Populat Hlth, Nicosia, Cyprus

[2] PlanAdapt, Berlin, Germany

[3] Univ Perugia, Sch Med, Dept Cardiol, Perugia, Italy

[4] Univ Limassol, Dept Informat Technol, Limassol, Cyprus

[5] MIT, Cambridge, MA USA

[6] Deakin Univ, Inst Hlth Transformat, Sch Hlth & Social Dev, Waurn Ponds, Australia

[7] Monash Univ, Monash Univ Disaster Resilience Initiat, Melbourne, Australia

[8] Med Univ Vienna, Ctr Publ Hlth, Dept Epidemiol, Vienna, Austria

[9] Univ Fed Rio De Janeiro, Inst Estudos Saude Colet, Rio De Janeiro, Brazil

[10] Univ Fed Fluminense, Dept Epidemiol, Inst Saude Colet, Niteroi, Brazil

[11] Hlth Monitoring Unit, Cyprus Minist Hlth, 1 Prodromou & 17 Chilonos St, CY-1448 Nicosia, Cyprus

[12] St Georges Univ London, Populat Hlth Res Inst, London, England

[13] Natl Ctr Dis Control & Publ Hlth, Med Stat, Tbilisi, Georgia

[14] Al Farabi Kazakh Natl Univ, Hlth Res Inst, Alma Ata, Kazakhstan

[15] Asfendiyarov Kazakh Natl Med Univ, Alma Ata, Kazakhstan

[16] Nazarbayev Univ, Sch Med, Astana, Kazakhstan

[17] Natl Inst Publ Hlth, Sch Publ Hlth, Ljubljana, Slovenia

[18] Univ Nicosia, Dept Med Sci, Nicosia, Cyprus

[19] Univ Nicosia, Dept Psychol, Nicosia, Cyprus

[20] Univ Nicosia, Nicosia, Cyprus

[21] Univ Nicosia, Med Sch, Nicosia, Cyprus

来源：

JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH | 2024年

关键词：

Cause-specific mortality; COVID-19; Cardiovascular diseases; Cancer; Respiratory tract infections; Public health measures; DEATHS;

D O I：

10.1007/s44197-024-00242-4

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background This study investigated cause-specific mortality rates in 12 countries during the COVID-19 pandemic in 2020 and 2021.Methods We collected weekly cause-specific mortality data from respiratory disease, pneumonia, cardiovascular disease (CVD) and cancer from national vital statistic databases. We calculated excess mortality for respiratory disease (excluding COVID-19 codes), pneumonia, and CVD in 2020 and 2021 by comparing observed weekly against expected mortality based on historical data (2015-2019), accounting for seasonal trends. We used multilevel regression models to investigate the association between country-level pandemic-related variables and cause-specific mortality.Results Significant reductions in cumulative mortality from respiratory disease and pneumonia were observed in 2020 and/or 2021, except for Georgia, Northern Ireland, Kazakhstan, and Ukraine, which exhibited excess mortality for one or both causes. Australia, Austria, Cyprus, Georgia, and Northern Ireland experienced excess cumulative CVD mortality in 2020 and/or 2021. Australia, Austria, Brazil, Cyprus, Georgia, Northern Ireland, Scotland and Slovenia, experienced increased crude cumulative cancer mortality during 2020 and/or 2021 compared to previous years. Among pandemic-related variables, reported COVID-19 incidence was negatively associated with increased cancer mortality, excess respiratory, (2020) and pneumonia (2021) mortality, and positively associated with respiratory and CVD mortality (2021). Stringency of control measures were negatively associated with excess respiratory disease, CVD, and increased cancer mortality (2021).Conclusions This study provides evidence of substantial excess mortality from CVD, and notable reductions in respiratory disease and pneumonia in both years across most countries investigated. Our study also highlights the beneficial impact of stringent control measures in mitigating excess mortality from most causes in 2021.

引用

页码：337 / 348

页数：12

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