Research Progress of 3D Printing Technology for Pharmaceutical Preparation

被引:0
作者
Tang L. [1 ]
Xie B. [1 ]
机构
[1] Key Laboratory of Advanced Manufacturing and Intelligent Technology, Harbin University of Science and Technology, Ministry of Education, Harbin
关键词
3D printing; 3D printing technology; extrusion 3D printing; inkjet 3D printing; laser 3D printing; Pharmaceutical preparation; printing stability; production quality;
D O I
10.2174/1872212118666230306091103
中图分类号
学科分类号
摘要
Pharmaceutical preparation is a kind of finished pharmaceutical product made by combining raw materials with various auxiliary materials in a certain form. At present, the field of pharmaceutical preparations can meet most drug needs, but there are some limitations. It is difficult to realize the production of personalized preparations. Because 3D printing technology has the ability of precise dose control and flexible shape customization, it can realize precise control of drug dosage, release behavior and local targeting in pharmaceutical preparations. Therefore, in medicine, 3D printing technology is increasingly used in the field of pharmaceutical preparations. 3D printing technology provides an important means for new drug printing and personalized drug customization of pharmaceutical preparations in the medical field. The 3D printing technology of drugs will inject fresh vitality into individualized drug delivery. Therefore, the development trend of 3D printing technology for pharmaceutical preparations has attracted more and more attention. In order to optimize the wide application of 3D printing technology in pharmaceutical preparation, 3D printing technology such as inkjet 3D printing technology, extrusion 3D printing technology and laser 3D printing technology were studied. In this paper, the selection, classification and introduction of 3D printing technology such as inkjet 3D printing technology, extrusion 3D printing technology and laser 3D printing technology in pharmaceutical preparations are reviewed. Through the investigation of various patents of 3D printing technology applied to pharmaceutical preparation in medicine, this paper summarizes and analyzes the main problems of 3D printing technology applied to pharmaceutical preparations, such as printing stability, production quality, etc. In addition, the development trend of 3D printing technology is also discussed. Optimization of various 3D printing technologies applied to pharmaceutical preparation in medicine is beneficial to improve printing stability and production quality in medicine. More related patents will be invented in the future. © 2024 Bentham Science Publishers.
引用
收藏
页码:127 / 139
页数:12
相关论文
共 112 条
[11]  
Cui M., Pan H., Fang D., Qiao S., Wang S., Pan W., Fabrication of high drug loading levetiracetam tablets using semi-solid extrusion 3D printing, J. Drug Deliv. Sci. Technol, 57, (2020)
[12]  
Tang L., Yang Y.D., Luo T., Application and research progress of 3D printing technology in medical and health fields, J. Modern Chinese Doctor, 28, pp. 165-168, (2016)
[13]  
Atheer A., Sarah J.T., Reshaping drug development using 3D printing, Drug Discov Today, 23, 8, pp. 1547-1555, (2018)
[14]  
Chen G.N., Shu H., Yu P., Application of 3D printing technology in pharmaceutical research, J. Chin. Pharm, 16, pp. 1353-1359, (2016)
[15]  
Shi J., Wang Z.M., Zheng A.P., Application and challenges of 3D printing technology in pharmaceutical preparations, J. Pharm. Prog, 3, pp. 164-173, (2019)
[16]  
He C., Tang Z., Tian H., Advances in 3D printing technology to prepare biomedical polymer materials, J. Acta Polym, 6, 52, pp. 722-732, (2013)
[17]  
Khaled S.A., Burley J.C., Alexander M.R., Yang J., Roberts C.J., 3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles, J. Control. Release, 217, pp. 308-314, (2015)
[18]  
Xiao Y.F., Wang B., Lin R., Progress in personalized drugs manufactured by 3D printing, J. Chin. Pharm, 52, 2, pp. 89-95, (2017)
[19]  
Wang X., Zhang C., Ping Q.N., Advances of 3D printing technology in advanced pharmaceutical preparations, Zhongguo Yaoke Daxue Xuebao, 47, 2, pp. 140-147, (2016)
[20]  
Palo M., Hollander J., Suominen J., Yliruusi J., Sandler N., 3D printed drug delivery devices: Perspectives and technical challenges, Expert Rev. Med. Devices, 14, 9, pp. 685-696, (2017)