Studying RNA dynamics from single-cell RNA sequencing snapshots

被引：0

作者：

Carilli, Maria ^{[1
]}

Pachter, Lior ^{[1
]}

机构：

[1] CALTECH, Pasadena, CA 91125 USA

来源：

NATURE METHODS | 2024年 / 21卷 / 08期

关键词：

D O I：

10.1038/s41592-024-02366-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Rapid advancements in transcriptomics have enabled the quantification of individual transcripts for thousands of genes in millions of single cells. By coupling a machine learning inference framework with biophysical models describing the RNA life cycle, we can explore the dynamics driving RNA production, processing and degradation across cell types.

引用

页码：1418 / 1419

页数：2

共 50 条

[21] Single-cell RNA sequencing of human kidney
Liao, Jinling
Yu, Zhenyuan
Chen, Yang
Bao, Mengying
Zou, Chunlin
Zhang, Haiying
Liu, Deyun
Li, Tianyu
Zhang, Qingyun
Li, Jiaping
Cheng, Jiwen
Mo, Zengnan
SCIENTIFIC DATA, 2020, 7 (01)
[22] Single-Cell RNA Sequencing of Childhood Medulloblastoma
Willard, N.
Riemondy, K.
Donson, A.
Venkataraman, S.
Sanford, B.
Sill, M.
Griesinger, A.
Amani, V.
Hankinson, T.
Handler, M.
Gershon, T.
Wechsler-Reya, R.
Hesselberth, J.
Garancher, A.
Foreman, N.
Vibhakar, R.
JOURNAL OF MOLECULAR DIAGNOSTICS, 2020, 22 (11): : S68 - S68
[23] Single-cell RNA sequencing in orthopedic research
Tao Wang
Ling Wang
Liping Zhang
Yubin Long
Yingze Zhang
Zhiyong Hou
Bone Research, 11
[24] Single-cell RNA sequencing of human kidney
Jinling Liao
Zhenyuan Yu
Yang Chen
Mengying Bao
Chunlin Zou
Haiying Zhang
Deyun Liu
Tianyu Li
Qingyun Zhang
Jiaping Li
Jiwen Cheng
Zengnan Mo
Scientific Data, 7
[25] Revolutionizing immunology with single-cell RNA sequencing
Haide Chen
Fang Ye
Guoji Guo
Cellular & Molecular Immunology, 2019, 16 : 242 - 249
[26] Experimental design for single-cell RNA sequencing
Baran-Gale, Jeanette
Chandra, Tamir
Kirschner, Kristina
BRIEFINGS IN FUNCTIONAL GENOMICS, 2018, 17 (04) : 233 - 239
[27] Single-cell RNA sequencing: An overview for the ophthalmologist
Rossin, Elizabeth J.
Sobrin, Lucia
Kim, Leo A.
SEMINARS IN OPHTHALMOLOGY, 2021, 36 (04) : 191 - 197
[28] Single-cell RNA sequencing in cancer research
Zhang, Yijie
Wang, Dan
Peng, Miao
Tang, Le
Ouyang, Jiawei
Xiong, Fang
Guo, Can
Tang, Yanyan
Zhou, Yujuan
Liao, Qianjin
Wu, Xu
Wang, Hui
Yu, Jianjun
Li, Yong
Li, Xiaoling
Li, Guiyuan
Zeng, Zhaoyang
Tan, Yixin
Xiong, Wei
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2021, 40 (01)
[29] Single-Cell RNA-Sequencing in Glioma
Johnson, Eli
Dickerson, Katherine L.
Connolly, Ian D.
Gephart, Melanie Hayden
CURRENT ONCOLOGY REPORTS, 2018, 20 (05)
[30] Single-cell RNA-sequencing of the brain
Duran, Raquel Cuevas-Diaz
Wei, Haichao
Wu, Jia Qian
CLINICAL AND TRANSLATIONAL MEDICINE, 2017, 6

← 1 2 3 4 5 →