Surgical treatment of atrial fibrillation in elderly patients undergoing high risk cardiac surgery

被引:0
作者
Uzzaman, Mohammed Mohsin [1 ]
Manoly, Imthiaz [1 ]
Pannikkar, Mohini [1 ]
Caruso, Vincenzo [1 ]
Matuszewski, Maciej [1 ]
Nikolaidis, Nicolas [1 ]
Billing, Stephen [1 ]
机构
[1] New Cross Hosp, Dept Cardiothorac Surg, Wolverhampton, England
关键词
Atrial fibrillation; Cox-Maze IV; Ablation; Elderly; Outcomes; Long-term; AORTIC-VALVE-REPLACEMENT; COX MAZE PROCEDURE; ABLATION; MORTALITY; ASSOCIATION; ARRHYTHMIA; PROGNOSIS; OUTCOMES; HISTORY; RHYTHM;
D O I
10.1186/s13019-024-02796-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BackgroundEvaluating outcomes of concurrent Cox-Maze procedures in elderly patients undergoing high-risk cardiac surgery.MehodsWe retrospectively identified patients aged over 70 years with Atrial Fibrillation (AF) from 2011 to 2017 who had two or more other cardiac procedures. They were subdivided into two groups: 1. Cox-Maze IV AF ablation. 2. No-Surgical AF treatment. A propensity match score was used to generate a homogeneous cohort and to eliminate confounding variables. Heart rhythm was assessed from Holter reports or 12-lead ECG. Follow-up data was collected through telephone consultations and medical records.ResultsThere were 239 patients. Median follow up was 61 months. 70 patients had Cox-Maze IV procedures (29.3%). Demographic, intra- and post-operative outcomes were similar between groups although duration of pre-operative AF was shorter in Cox-Maze group (p = 0.001). There was no significant 30-day mortality difference in propensity matched cohorts (n = 84. P = 0.078). Sinus rhythm at annual and latest follow-up was 84.9% and 80.0% respectively in Maze group - 160 patients (66.9%) were alive at long-term follow-up with good survival outcomes in Cox Maze group. There was a high proportion of patients in NYHA 1 status in Cox-Maze group. No differences observed in freedom from stroke (p = 0.80) or permanent pacemaker (p = 0.33) between the groups.ConclusionsSurgical ablation is beneficial in elderly patients undergoing high-risk surgery - promoting excellent long-term freedom from AF and symptomatic / prognostic benefits, without added risk. Therefore, surgical risk should not be reason to deny benefits of concomitant AF-ablation.Clinical trial registrationNot required.
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页数:8
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共 29 条
  • [1] Ad N, 2013, J CARDIOVASC SURG, V54, P281
  • [2] Association of operative risk with the outcome of concomitant Cox Maze procedure: A comparison of results across risk groups
    Ad, Niv
    Holmes, Sari D.
    Pritchard, Graciela
    Shuman, Deborah J.
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2014, 148 (06) : 3027 - 3033
  • [3] The association between early atrial arrhythmia and long-term return to sinus rhythm for patients following the Cox maze procedure for atrial fibrillation
    Ad, Niv
    Henry, Linda
    Holmes, Sari D.
    Stone, Lori E.
    Hunt, Sharon
    [J]. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2013, 44 (02) : 295 - 301
  • [4] Does preoperative atrial fibrillation increase the risk for mortality and morbidity after coronary artery bypass grafting?
    Ad, Niv
    Barnett, Scott D.
    Haan, Constance K.
    O'Brien, Sean M.
    Milford-Beland, Sarah
    Speir, Alan M.
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2009, 137 (04) : 901 - 906
  • [5] Long-Term Natural History of Adult Wolff-Parkinson-White Syndrome Patients Treated With and Without Catheter Ablation
    Bunch, T. Jared
    May, Heidi T.
    Bair, Tami L.
    Anderson, Jeffrey L.
    Crandall, Brian G.
    Cutler, Michael J.
    Jacobs, Victoria
    Mallender, Charles
    Muhlestein, Joseph B.
    Osborn, Jeffrey S.
    Weiss, J. Peter
    Day, John D.
    [J]. CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2015, 8 (06) : 1465 - 1471
  • [6] HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: Recommendations for personnel, policy, procedures and follow-up
    Calkins, Hugh
    Brugada, Josep
    Packer, Douglas L.
    Cappato, Riccardo
    Chen, Shih-Ann
    Crijns, Harry J. G.
    Damiano, Ralph J., Jr.
    Davies, D. Wyn
    Haines, David E.
    Haissaguerre, Michel
    Lesaka, Yoshito
    Jackman, Warren
    Jais, Pierre
    Kottkamp, Hans
    Kuck, Karl Heinz
    Lindsay, Bruce D.
    Marchlinski, Francis E.
    McCarthy, Patrick M.
    Mont, J. Lluis
    Morady, Fred
    Nademanee, Koonlawee
    Natale, Andrea
    Pappone, Carlo
    Prystowsky, Eric
    Raviele, Antonio
    Ruskin, Jeremy N.
    Shemin, Richard J.
    [J]. EUROPACE, 2007, 9 (06): : 335 - 379
  • [7] Calkins H, 2018, EUROPACE, V20, pE1, DOI [10.1093/europace/eux274, 10.1016/j.hrthm.2017.05.012, 10.1093/europace/eux275]
  • [8] THE SURGICAL-TREATMENT OF ATRIAL-FIBRILLATION .3. DEVELOPMENT OF A DEFINITIVE SURGICAL-PROCEDURE
    COX, JL
    SCHUESSLER, RB
    DAGOSTINO, HJ
    STONE, CM
    CHANG, BC
    CAIN, ME
    CORR, PB
    BOINEAU, JP
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1991, 101 (04) : 569 - 583
  • [9] Intraoperative options for treating atrial fibrillation associated with mitral valve disease
    Cox, JL
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2001, 122 (02) : 212 - 215
  • [10] The long-term outcome of patients with coronary disease and atrial fibrillation undergoing the Cox maze procedure
    Damiano, RJ
    Gaynor, SL
    Bailey, M
    Prasad, S
    Cox, JL
    Boineau, JP
    Schuessler, RP
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2003, 126 (06) : 2016 - 2021