Antibacterial Activity of Anatase TiO2 Added Cu Powder

被引：0

作者：

Hirota K. ^{[1
]}

Jinzenji A. ^{[2
]}

Tsukagoshi K. ^{[2
]}

Taniguchi Y. ^{[3
]}

Kawakami H. ^{[3
]}

Ozawa T. ^{[4
]}

Wada M. ^{[4
]}

Yuki Y. ^{[5
]}

机构：

[1] Research Center of Bio-Micro-Fluidic Science, Doshisha University, 1-3 Tatara Miyakodani, Kyotanabe

[2] Department of Chemical Engineering and Materials Science, Faculty of Science & Engineering, Doshisha University, 1-3 Tatara Miyakodani, Kyotanabe

[3] Graduate School of Engineering, College of Engineering, Osaka Metropolitan University, 3-3-138 Sugimoto Sumiyoshi-ku, Osaka

[4] Japan Copper Development Association, 1-1-10 Ueno Taito-ku, Tokyo

[5] Japan Copper and Brass Association, 1-1-10 Ueno Taito-ku, Tokyo

来源：

Funtai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy | 2023年 / 70卷 / 03期

关键词：

anatase TiO[!sub]2[!/sub; antibacterial activity; copper powder; heat treatment; reactive oxygen species (ROS);

D O I：

10.2497/jjspm.70.121

中图分类号：

学科分类号：

摘要：

To understand the mechanism of antibacterial activity of bulk Cu, N2-atomized Cu powder has been used instead. It was heated from 425 to 673 K in air for 4.2 • 102 s and measured by XRD and Chemi-luminescence (CL) to determine the contents of Cu2O and CuO, and reactive oxygen species (ROS), respectively; ROS being much affected by Cu2O and CuO can play a role to kill bacteria. Cu2O increased from 3.3 mass% (R.T.) to around 20% (673 K), however, CuO was almost constant (1.2~3.5%). High CL intensity was observed for Cu powders heated at 598~673 K. Then, a small amount of anatase TiO2 (a-TiO2) was added and heated at 673 K for 4.2 • 102 s in air, 1% O2-99% N2, and N2. The powder heated under 1% O2 showed the high CL intensity summation (∑CL), especially, 8.0 mol% a-TiO2 added and heated sample (“8.0Ti powder”) gave the about 4.7 times higher ∑CL than the starting material. ESR results using the spin-trap method showed that they contained hydroxyl radical •OH and its intensity increased from starting material to “8.0Ti powder”. However, bio-test proved that these samples revealed the same antibiotic activity. Formation mechanism of ROS (•OH and super oxide radical •O2-) on the surfaces of Cu/Cu2O/CuO has been proposed. ©2023 Japan Society of Powder and Powder Metallurgy.

引用

页码：121 / 131

页数：10

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