Pharmacology of caffeine and its effects on the human body

被引:23
|
作者
Reddy, Vundrala Sumedha [1 ]
Shiva, S. [1 ,2 ]
Manikantan, Srinidhi [1 ]
Ramakrishna, Seeram [1 ]
机构
[1] Natl Univ Singapore, Ctr Nanotechnol & Sustainabil, Dept Mech Engn, Singapore 117574, Singapore
[2] Vellore Inst Technol, Sch Biosci & Technol, Vellore 632014, India
关键词
Caffeine; Pharmacological effects; Pharmacokinetics; Mechanism; Pregnancy; Drug delivery; BLOOD-PRESSURE; DRUG-DELIVERY; ANTIOXIDANT PROPERTIES; CONSUMPTION; COFFEE; PREGNANCY; SYSTEM; METABOLISM; ANTIBACTERIAL; DISPOSITION;
D O I
10.1016/j.ejmcr.2024.100138
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Caffeine is the world's most popular stimulant and psychoactive substance. Given the ubiquitous use of caffeine, it is crucial for us to comprehend how our body interacts with caffeine. The pharmacokinetics of caffeine and its action mechanisms have been reviewed in this paper. The safety and recommended dosage of caffeine in healthy adults and vulnerable populations like children and pregnant women are also discussed in this paper. While caffeine consumption is generally safe, this review paper also examines the potential effects that caffeine could have on human health and development. Studies indicated that caffeine exhibits neuroprotective properties, potentially serving as a preventive measure against the onset of neurodegenerative conditions such as Alz-heimer's and Parkinson's disease. The article also explores various physiological effects of caffeine on the body, in addition to investigating novel drug delivery techniques, particularly nano-delivery systems designed to efficiently administer caffeine.
引用
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页数:14
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