Preparation and release properties of functional emulsion based on hyaluronic acid self-assembled colloidal particles

被引：0
|
作者：
Fan X. [1 ]
Yan X. [1 ]
Yang H. [1 ]
Lin H. [1 ]
Xu M. [1 ]
Zhang C. [1 ]
机构：
[1] School of Chemical and Environmental Engineering, Anhui Polytechnic University, Wuhu
来源：
Fuhe Cailiao Xuebao/Acta Materiae Compositae Sinica | 2023年 / 40卷 / 10期
基金：
中国国家自然科学基金;
关键词：
bio-macromolecule; colloidal nanoparticles; functional emulsion; self-assembly; sustained-release;
D O I：
10.13801/j.cnki.fhclxb.20230118.001
中图分类号：
学科分类号：
摘要：
Functional emulsion is one of the hot topics because of their functional factors. Bio-macromolecules hyaluronic acid (HA), lysozyme (Lys) and trace metal element zinc can self-assemble to prepare Lys-Zn2+/HA colloidal particles by electrostatic interaction. The effects of different raw material concentration on the properties of colloidal particles were studied to obtain colloidal nanoparticles under optimal assembly conditions. The size and morphology of the colloidal particles were characterized by nanometer particle size analyzer and scanning electron microscope. The results show that the formed colloidal particles have a spherical structure with a particle size of about 300 nm. The colloidal particles have surface activity and can be reassembled at the oil (containing fat-soluble vitamin D3)-water interface to stabilize oil-in-water functional Pickering emulsions. The effects of pH and salt concentration on the properties and emulsifying properties of colloidal particles were investigated in detail. The sustained release properties of the emulsion to trace metals and vitamin D3 functional factors were studied with the optimum emulsion performance. The results show that the emulsion has a certain sustained-release performance for both water-soluble and fat-soluble functional factors and has potential applications in the fields of food, medicine and cosmetics. © 2023 Beijing University of Aeronautics and Astronautics (BUAA). All rights reserved.
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页码：5803 / 5810
页数：7
相关论文
共 22 条
  • [1] ZHAO Q L, XIE T T, HONG X, Et al., Modification of functional properties of perilla protein isolate by high-intensity ultrasonic treatment and the stability of O/W emulsion[J], Food Chemistry, 368, (2021)
  • [2] SINGH C K S, LIM H P, TEY B T, Et al., Spray-dried alginate-coated Pickering emulsion stabilized by chitosan for improved oxidative stability and in vitro release profile[J], Carbohydrate Polymers, 251, (2021)
  • [3] DELSHADI R, BAHRAMI A, TAFTI A G, Et al., Micro and nano-encapsulation of vegetable and essential oils to develop functional food products with improved nutritional profiles[J], Trends in Food Science & Technology, 104, pp. 72-83, (2020)
  • [4] YANG J, ZHOU Q W, HUANG Z H, Et al., Mechanisms of in vitro controlled release of astaxanthin from starch-based double emulsion carriers[J], Food Hydrocolloids, 119, (2021)
  • [5] GUO J, JIANG J G, GU X L, Et al., Encapsulation of βcarotene in calcium alginate hydrogels templated by oil-in-water-in-oil (O/W/O) double emulsions[J], Colloids and Surfaces A: Physicochemical and Engineering Aspects, 608, (2021)
  • [6] SNOUSSI A, CHOUAIBI M, BOUZOUITA N, Et al., Microencapsulation of catechin using water-in-oil-in-water (W<sub>1</sub>/O/W<sub>2</sub>) double emulsions: Study of release kinetics, rheological, and thermodynamic properties[J], Journal of Molecular Liquids, 311, (2020)
  • [7] LAMBA H, SATHISH K, SABIKHI L., Double emulsions: Emerging delivery system for plant bioactives[J], Food and Bioprocess Technology, 8, 4, pp. 709-728, (2015)
  • [8] WHITESIDES G M, GRZYBOWSKI B., Self-assembly at all scales[J], Science, 295, 5564, pp. 2418-2421, (2002)
  • [9] FUJII S, CAI Y L, WEAVER J V M, Et al., Syntheses of shell cross-linked micelles using acidic ABC triblock copolymers and their application as pH-responsive particulate emulsifiers[J], Journal of the American Chemical Society, 127, 20, pp. 7304-7305, (2005)
  • [10] YI C L, YANG Y Q, ZHU Y, Et al., Self-assembly and emulsification of poly {[styrene-alt-maleic acid]-co-[styrene-alt(N-3, 4-dihydroxyphenylethyl-maleamic acid)]}[J], Langmuir, 28, 25, pp. 9211-9222, (2012)
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