A single-use cartridge based on an acoustic sensor for a portable device for rapid assessment of the functional state of the hemostasis system

被引：0

作者：

Zhukov, E. L. ^{[1
]}

Slizevich, D. S. ^{[1
,2
]}

Gubarev, F. A. ^{[1
]}

Nagornyi, O. A. ^{[2
]}

Zyryanov, S. V. ^{[2
]}

机构：

[1] Natl Res Tomsk Polytech Univ, Res Sch Chem & Biomed Technol, Tomsk, Russia

[2] OOO Mednord T, Tomsk, Russia

来源：

BIOMEDICAL ENGINEERING | 2024年 / 58卷 / 02期

关键词：

Piezoelectricity;

D O I：

10.1007/s10527-024-10375-2

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

This paper presents results from the development of a disposable piezoelectric sensor and a cartridge based on it for a portable device for rapid assessment of the functional state of the hemostasis system based on analysis of native capillary blood. The design of a disposable piezoelectric sensor and the resonant frequency for studies of the human blood coagulation system were selected. Results obtained from tests of the method and device using normal plasma and native capillary blood showed that results were reproducible, indicating that there is promise in employing acoustic effects to study the properties of blood and to develop portable devices based on them for operation in the "point-of-care" mode. Analyte volume is 20-25 mu l, which makes the device convenient for use outside medical institutions.

引用

页码：102 / 105

页数：4

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