Histone methylation in Epstein-Barr virus-associated diseases

被引：1
作者：
Chen, Guanglian [1 ,2 ]
Zhang, Linlin [1 ,2 ]
Wang, Ran [1 ,2 ]
Xie, Zhengde [1 ,2 ]
机构：
[1] Capital Med Univ, Beijing Childrens Hosp, Beijing Pediat Res Inst, Natl Clin Res Ctr Resp Dis,Minist Educ,Natl Ctr Ch, Beijing 100045, Peoples R China
[2] Chinese Acad Med Sci, Res Unit Crit Infect Children, 2019RU016, Beijing 100045, Peoples R China
来源：
EPIGENOMICS | 2024年 / 16卷 / 11-12期
基金：
芬兰科学院;
关键词：
EBV-associated gastric cancer; histone methylation; infectious mononucleosis; lymphoma; nasopharyngeal carcinoma; CELL LYMPHOMA; TRANSCRIPTIONAL REGULATION; EZH2; INHIBITION; BZLF1; PROMOTER; OPEN-LABEL; CARCINOMA; EBV; TAZEMETOSTAT; EXPRESSION; LATENCY;
D O I：
10.1080/17501911.2024.2345040
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Epstein-Barr virus (EBV) infection is linked to various human diseases, including both noncancerous conditions like infectious mononucleosis and cancerous diseases such as lymphoma and nasopharyngeal carcinoma. After the initial infection, EBV establishes a lifelong presence and remains latent in specific cells. This latent infection causes changes in the epigenetic marks known as histone methylation. Many studies have examined the role of histone methylation in different EBV-associated diseases, and understanding how EBV affects histone methylation can help us identify potential targets for epigenetic therapies. This review focuses on the research progress made in understanding histone methylation in well-studied EBV-associated diseases, intending to provide insights into potential strategies based on histone methylation to combat EBV-related ailments.
引用
收藏
页码：865 / 877
页数：13
相关论文
共 117 条
  • [1] EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation
    Adamik, Juraj
    Jin, Shunqian
    Sun, Quanhong
    Zhang, Peng
    Weiss, Kurt R.
    Anderson, Judith L.
    Silbermann, Rebecca
    Roodman, G. David
    Galson, Deborah L.
    [J]. MOLECULAR CANCER RESEARCH, 2017, 15 (04) : 405 - 417
  • [2] Diagnosis and Management of Rheumatoid Arthritis A Review
    Aletaha, Daniel
    Smolen, Josef S.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2018, 320 (13): : 1360 - 1372
  • [3] Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation
    Alinari, Lapo
    Mahasenan, Kiran V.
    Yan, Fengting
    Karkhanis, Vrajesh
    Chung, Ji-Hyun
    Smith, Emily M.
    Quinion, Carl
    Smith, Porsha L.
    Kim, Lisa
    Patton, John T.
    Lapalombella, Rosa
    Yu, Bo
    Wu, Yun
    Roy, Satavisha
    De Leo, Alessandra
    Pileri, Stefano
    Agostinelli, Claudio
    Ayers, Leona
    Bradner, James E.
    Chen-Kiang, Selina
    Elemento, Olivier
    Motiwala, Tasneem
    Majumder, Sarmila
    Byrd, John C.
    Jacob, Samson
    Sif, Said
    Li, Chenglong
    Baiocchi, Robert A.
    [J]. BLOOD, 2015, 125 (16) : 2530 - 2543
  • [4] The molecular hallmarks of epigenetic control
    Allis, C. David
    Jenuwein, Thomas
    [J]. NATURE REVIEWS GENETICS, 2016, 17 (08) : 487 - 500
  • [5] PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia
    Aries, Ingrid M.
    Bodaar, Kimberly
    Karim, Salmaan A.
    Chonghaile, Triona Ni
    Hinze, Laura
    Burns, Melissa A.
    Pfirrmann, Maren
    Degar, James
    Landrigan, Jack T.
    Balbach, Sebastian
    Peirs, Sofie
    Menten, Bjorn
    Isenhart, Randi
    Stevenson, Kristen E.
    Neuberg, Donna S.
    Devidas, Meenakshi
    Loh, Mignon L.
    Hunger, Stephen P.
    Teachey, David T.
    Rabin, Karen R.
    Winter, Stuart S.
    Dunsmore, Kimberly P.
    Wood, Brent L.
    Silverman, Lewis B.
    Sallan, Stephen E.
    Van Vlierberghe, Pieter
    Orkin, Stuart H.
    Knoechel, Birgit
    Letai, Anthony G.
    Gutierrez, Alejandro
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2018, 215 (12) : 3094 - 3114
  • [6] An Atlas of the Epstein-Barr Virus Transcriptome and Epigenome Reveals Host-Virus Regulatory Interactions
    Arvey, Aaron
    Tempera, Italo
    Tsai, Kevin
    Chen, Horng-Shen
    Tikhmyanova, Nadezhda
    Klichinsky, Michael
    Leslie, Christina
    Lieberman, Paul M.
    [J]. CELL HOST & MICROBE, 2012, 12 (02) : 233 - 245
  • [7] Histone Modifications and Cancer
    Audia, James E.
    Campbell, Robert M.
    [J]. COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2016, 8 (04):
  • [8] Transcriptional and epigenetic modulation of autophagy promotes EBV oncoprotein EBNA3C induced B-cell survival
    Bhattacharjee, Shaoni
    Bose, Priyanka
    Patel, Krishna
    Roy, Shatadru Ghosh
    Gain, Chandrima
    Gowda, Harsha
    Robertson, Erle S.
    Saha, Abhik
    [J]. CELL DEATH & DISEASE, 2018, 9
  • [9] Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis
    Bjornevik, Kjetil
    Cortese, Marianna
    Healy, Brian C.
    Kuhle, Jens
    Mina, Michael J.
    Leng, Yumei
    Elledge, Stephen J.
    Niebuhr, David W.
    Scher, Ann, I
    Munger, Kassandra L.
    Ascherio, Alberto
    [J]. SCIENCE, 2022, 375 (6578) : 296 - +
  • [10] EZH2 Inhibition by Tazemetostat Results in Altered Dependency on B-cell Activation Signaling in DLBCL
    Brach, Dorothy
    Johnston-Blackwell, Danielle
    Drew, Allison
    Lingaraj, Trupti
    Motwani, Vinny
    Warholic, Natalie M.
    Feldman, Igor
    Plescia, Christopher
    Smith, Jesse J.
    Copeland, Robert A.
    Keilhack, Heike
    Chan-Penebre, Elayne
    Knutson, Sarah K.
    Ribich, Scott A.
    Raimondi, Alejandra
    Thomenius, Michael J.
    [J]. MOLECULAR CANCER THERAPEUTICS, 2017, 16 (11) : 2586 - 2597
12345678910