Infective endocarditis and antithrombotic therapy

被引:0
作者
Morelli, Cristina [1 ]
Rocca, Bianca [2 ]
Gigante, Bruna [3 ,4 ]
机构
[1] Univ Florence, NeuroFarBa Dept, Florence, Italy
[2] Catholic Univ, Sch Med, Dept Safety & Bioeth, Rome, Italy
[3] Karolinska Inst, Dept Med, Div Cardiovasc Med, Stockholm, Sweden
[4] Karolinska Inst, Div Cardiovasc Med, Stockholm, Sweden
基金
瑞典研究理事会;
关键词
Infective endocarditis; anticoagulant; antiplatelet drugs; bleeding; EMBOLIC EVENTS; INTRACRANIAL HEMORRHAGE; STAPHYLOCOCCUS-AUREUS; ANTIPLATELET THERAPY; RISK; COMPLICATIONS; MANAGEMENT; ASPIRIN; MECHANISMS; THROMBOSIS;
D O I
10.1159/000538549
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Incidence of infective endocarditis (IE) is progressively raising because of the increasing number of cardiovascular invasive procedures, support treatment and devices, awareness in the medical community and improved diagnostic modalities. IE pathophysiology is a unique model of immunothrombosis and the clinical course is often complicated by either thromboembolic or hemorrhagic events. Managing antithrombotic treatment is challenging and the level of supporting evidence scant. Aim of this review was to discuss and present the thromboembolic and bleeding complication associated with IE and review the available evidence on anti-thrombotic treatment in patients with IE with and without a previous indication to anti-thrombotic drugs.
引用
收藏
页码:513 / 522
页数:10
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