Vitamin D and Dyslipidemia: Is There Really a Link? A Narrative Review

被引:10
作者
Al Refaie, Antonella [1 ,2 ]
Baldassini, Leonardo [1 ]
Mondillo, Caterina [1 ]
De Vita, Michela [1 ]
Giglio, Elisa [1 ]
Tarquini, Roberto [2 ]
Gonnelli, Stefano [1 ]
Caffarelli, Carla [1 ]
机构
[1] Univ Siena, Dept Med Surg & Neurosci, Sect Internal Med, I-53100 Siena, Italy
[2] San Giuseppe Hosp, Div Internal Med 1, I-50053 Tuscany, Italy
关键词
vitamin D; dyslipidemia; cardiovascular prevention; cholesterol; triglycerides; CARDIOVASCULAR RISK-FACTORS; TYPE-2; DIABETIC-PATIENTS; RECEPTOR GENE POLYMORPHISMS; RANDOMIZED CONTROLLED-TRIAL; D SUPPLEMENTATION; LIPID PROFILE; DOUBLE-BLIND; INSULIN-RESISTANCE; METABOLIC SYNDROME; SERUM-LIPIDS;
D O I
10.3390/nu16081144
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Nowadays, the interest in the extraskeletal effects of vitamin D is growing. In the literature, its several possible actions have been confirmed. Vitamin D seems to have a regulatory role in many different fields-inflammation, immunity, and the endocrine system-and many studies would demonstrate a possible correlation between vitamin D and cardiovascular disease. In this paper, we deepened the relationship between vitamin D and dyslipidemia by reviewing the available literature. The results are not entirely clear-cut: on the one hand, numerous observational studies suggest a link between higher serum vitamin D levels and a beneficial lipid profile, while on the other hand, interventional studies do not demonstrate a significant effect. Understanding the possible relationship between vitamin D and dyslipidemia may represent a turning point: another link between vitamin D and the cardiovascular system.
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页数:34
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