The Fascinating Interplay between Growth Hormone, Insulin-Like Growth Factor-1, and Insulin

被引：17
作者：
Nijenhuis-Noort, Eline C. [1 ]
Berk, Kirsten A. [1 ]
Neggers, Sebastian J. C. M. M. [1 ]
van der Lely, Aart J. [1 ,2 ]
机构：
[1] Erasmus MC Univ, Div Endocrinol, Dept Internal Med, Med Ctr, Rotterdam, Netherlands
[2] Erasmus Univ, Dept Med, Div Endocrinol, Med Ctr, Dr Molewaterpl 40, NL-3015 GD Rotterdam, Netherlands
来源：
ENDOCRINOLOGY AND METABOLISM | 2024年 / 39卷 / 01期
关键词：
Humans; Insulin; Growth hormone; Acromegaly; Insulin-like growth factor I; Diabetes mellitus; type; 1; Diabetes melli- tus; 2; human; Liver cirrhosis; MUSCLE; LONG; PEGVISOMANT; RESISTANCE; COMPLEX; GLUCOSE; DIET; GH;
D O I：
10.3803/EnM.2024.101
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This review intends to provide the reader with a practical overview of several (patho)physiological conditions in which knowledge of the interplay between growth hormone (GH), insulin-like growth factor-1 (IGF-1), and insulin is important. This might help treating physicians in making the right decisions on how to intervene and improve metabolism for the benefit of patients, and to understand why and how metabolism responds in their specific cases. We will specifically address the interplay between GH, IGF-1, and insulin in type 1 and 2 diabetes mellitus, liver cirrhosis, and acromegaly as examples in which this knowledge is truly necessary.
引用
收藏
页码：83 / 89
页数：7
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