Synthesis and Degradation Characterization of Intelligent Hydrogels Cross-Linked by N-Maleyl Chitosan

被引：0
|
作者：
Liu X. [1 ]
Sui M. [1 ]
Zhao C. [1 ]
Yu Y. [1 ]
机构：
[1] Key Laboratory of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao
来源：
Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering | 2019年 / 35卷 / 12期
关键词：
Chitosan; Compressive strength; Degradation; PolyN-isopropyl acrylamide hydrogel; Thermoresponsive;
D O I：
10.16865/j.cnki.1000-7555.2019.0313
中图分类号：
学科分类号：
摘要：
The natural product chitosan modified with maleic anhydride was introduced into the thermoresponsive hydrogels, poly N-isopropyl acrylamide (PNIPAAm). Effect of N-malay acylation chitosan (N-MACH) on the thermoresponsive, swelling, compressive strength, and degradation of the hydrogels was investigated. The results suggest that when the content of N-MACH is 30%, the synthesized hydrogels not only have better temperature sensitivity and swelling performance, but also have a compression strength 311.2% higher than that of PNIPAAm hydrogels only crosslinked with BIS. In enzymatic degradation, the mass loss of the hydrogel with 30% N-MACH could be added up to 60.8% in the solution of cellulase (8 U/mL) at 40℃ and pH 5.0, which furtherly provide the foundation for the application of chitosan crosslinked hydrogels in the biological field. © 2019, Editorial Board of Polymer Materials Science & Engineering. All right reserved.
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页码：138 / 142
页数：4
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