Management and Pharmacological Treatment of Peripheral Arterial Disease

被引:3
作者
Leatham, Samantha J. [1 ]
Winckel, Karl R. [1 ,2 ]
De Guzman, Keshia R. [1 ,2 ]
机构
[1] Princess Alexandra Hosp, Dept Pharm, 199 Ipswich Rd, Brisbane, Qld 4102, Australia
[2] Univ Queensland, Sch Pharm, Brisbane, Qld, Australia
关键词
peripheral arterial disease; revascularisation; pharmacological management; antithrombotic therapy; CONVERTING-ENZYME-INHIBITOR; AMPUTATION-FREE SURVIVAL; DRUG-COATED BALLOON; INTERMITTENT CLAUDICATION; HIGH-RISK; CARDIOVASCULAR EVENTS; ELUTING STENT; TRIAL; ANGIOPLASTY; ASSOCIATION;
D O I
10.1177/08971900241250084
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Background: Peripheral arterial disease (PAD) is a complex, heterogeneous condition that has become a leading health concern globally. Peripheral arterial disease often co-exists with other vascular disease states, including cerebrovascular and cardiovascular disease. Optimal therapy for managing symptoms and progression of disease employs non-pharmacological, pharmacological, and contemporary revascularisation techniques to improve clinical outcomes and quality of life. However, large well-designed randomised control trials (RCT) and corresponding evidence-based guidelines for management of PAD are lacking, with current practice standards often extrapolated from evidence in coronary artery disease.Purpose: This review article aims to discuss currently accepted best pharmacological practice for PAD.Method: Relevant articles were searched between May 2023 and January 2024 through PubMed, Cochrane Library, Google Scholar and international guidelines, focusing on pharmacological management for PAD.Results: This narrative review discusses holistic pharmacological treatments for PAD.
引用
收藏
页码:1337 / 1345
页数:9
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