The complete genome of equid herpesvirus-1 (EHV-1) field isolates from Argentina reveals an interspecific recombinant strain

被引：0

作者：

Tau, Rocio Lucia ^{[1
]}

Marandino, Ana Eugenia ^{[2
]}

Panzera, Yanina ^{[2
]}

Alamos, Florencia ^{[1
,3
]}

Vissani, Maria Aldana ^{[1
,3
]}

Romera, Sonia Alejandra ^{[1
,3
]}

Perez, Ruben ^{[2
]}

Maidana, Silvina Soledad ^{[1
,3
]}

机构：

[1] Inst Virol & Technol Innovat Dr Nicolas Repetto &, IVIT INTA CONICET, RA-1686 Buenos Aires, Argentina

[2] Univ Republica, Fac Sci, Biol Inst, Evolutionary Genet Sect, Montevideo, Uruguay

[3] Univ Salvador, Vet Res Inst, Fac Agr & Vet Sci, Buenos Aires, Argentina

来源：

VIRUS GENES | 2024年 / 60卷 / 05期

关键词：

Horse; Herpesvirus; Recombination; Argentina; ICP4; DNA;

D O I：

10.1007/s11262-024-02093-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The Equid alphaherpesvirus type 1 (EHV-1) infection can have devastating economic consequences in the horse industry due to large-scale outbreaks of abortions, perinatal foal mortality, and myeloencephalopathy. The present study analyzed the genome of two isolates obtained from aborted fetuses in Argentina, E/745/99 and E/1297/07. The E745/99 genome shares 98.2% sequence identity with Ab4, a reference EHV-1 strain. The E/1297/07 genome shares 99.8% identity with NY03, a recombinant strain containing part of ORF64 and part of the intergenic region from Equid alphaherpesvirus-4 (EHV-4). The E/1297/07 genome has the same breakpoints as other United States and Japanese recombinants, including NY03. The recombinant regions have varying numbers of tandem repeat sequences and different minor parental sequences (EHV-4), suggesting distinct origins of the recombinant events. These are the first complete genomes of EHV-1 from Argentina and South America available in the Databases.

引用

页码：559 / 562

页数：4

共 16 条

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