A proof of concept: digital diary using 24-hour monitoring using wearable device for patients with Parkinson's disease in nursing homes

被引：1

作者：

Kamo, Hikaru ^{[1
]}

Oyama, Genko ^{[1
,2
,3
,4
,5
]}

Yamasaki, Yui ^{[6
]}

Nagayama, Tomohiro ^{[6
]}

Nawashiro, Ryotatsu ^{[6
]}

Hattori, Nobutaka ^{[1
,2
,3
,4
,5
,7
,8
]}

机构：

[1] Juntendo Univ, Sch Med, Dept Neurol, Tokyo, Japan

[2] Juntendo Univ, Dept Home Med Care Syst, Based Informat & Commun Technol, Grad Sch Med, Tokyo, Japan

[3] Juntendo Univ, Grad Sch Med, Dept Drug Dev Parkinsons Dis, Tokyo, Japan

[4] Juntendo Univ Grad Sch Med, Dept Probased Integrated Data Anal Neurol Disorder, Grad Sch Med, Tokyo, Japan

[5] Juntendo Univ, Res & Therapeut Movement Disorders, Grad Sch Med, Tokyo, Japan

[6] Sunwels Co Ltd, Chiyoda Ku, Tokyo, Japan

[7] Juntendo Univ, Res Inst Dis Old Age, Grad Sch Med, Tokyo, Japan

[8] RIKEN, Ctr Brain Sci, Neurodegenerat Disorders Collaborat Lab, Saitama, Japan

来源：

FRONTIERS IN NEUROLOGY | 2024年 / 15卷

关键词：

Parkinson's disease; wearable device; physiological biomarker; heart rate; wearing off; dyskinesia; DEEP BRAIN-STIMULATION; OSCILLATORY ACTIVITY; SUBTHALAMIC NUCLEUS; TECHNOLOGIES; BRADYKINESIA; DYSKINESIA; LEVODOPA; PHASE;

D O I：

10.3389/fneur.2024.1356042

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction In the advanced stages of Parkinson's disease (PD), motor complications such as wearing-off and dyskinesia are problematic and vary daily. These symptoms need to be monitored precisely to provide adequate care for patients with advanced PD.Methods This study used wearable devices to explore biomarkers for motor complications by measuring multiple biomarkers in patients with PD residing in facilities and combining them with lifestyle and clinical assessments. Data on the pulse rate and activity index (metabolic equivalents) were collected from 12 patients over 30 days.Results The pulse rate and activity index during the off- and on-periods and dyskinesia were analyzed for two participants; the pulse rate and activity index did not show any particular trend in each participant; however, the pulse rate/activity index was significantly greater in the off-state compared to that in the dyskinesia and on-states, and this index in the dyskinesia state was significantly greater than that in the on-state in both participants.Conclusion These results suggest the pulse rate and activity index combination would be a useful indicator of wearing-off and dyskinesia and that biometric information from wearable devices may function as a digital diary. Accumulating more cases and collecting additional data are necessary to verify our findings.

引用

页数：7

共 37 条

[31] MEDIUM AND LONG LATENCY EMG RESPONSES IN LEG MUSCLES - PARKINSONS-DISEASE [J].