Anti-NMDAR encephalitis in a 19 year old female patient with ovarian teratoma: A case report

被引：3

作者：

El Hanna, Johnny ^{[1
]}

Quenum, Codjo ^{[1
]}

Arsalane, Abdelilah ^{[1
]}

机构：

[1] Grand Hop Est Francilien, Dept Obstet & Gynecol, Meaux, Seine & Marne, France

来源：

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY-X | 2021年 / 11卷

关键词：

Encephalitis; Autoimmune; Anti-N-Methyl-D-Aspartate; Ovarian teratoma;

D O I：

10.1016/j.eurox.2021.100129

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Background: Anti-N-Methyl-D-Aspartate encephalitis is a subcategory of auto-immune encephalitis. It is known for its aggressive presenting symptoms and rapid deterioration, yet it is treatment responsive. It is associated in 50 % to ovarian teratoma. Case: We report the case of a 19 year old female patient presenting for a psychiatric disorder of sudden onset with rapid deterioration. Neurologic imaging was in favor of encephalitis, and CSF studies revealed Anti NMDA receptors. Further abdominal imaging showed a right ovarian teratoma of 4 cm. Laparoscopic ovarian cyst resection was done, and corticotherapy, IVIG and anticonvulsants were given. We report complete resolution of symptoms after 7 months. Conclusion: Anti-NMDA receptor encephalitis with ovarian teratoma is a rare entity with rapid deterioration. Early diagnosis, surgical resection and proper medical treatment are essential for the management of this disease. (c) 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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